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Release Profiles of Dyes and Proteins from Calcium Phosphate Microspheres with Different Crystalline Phases
http://hdl.handle.net/10228/00008345
http://hdl.handle.net/10228/0000834571c4c8f1-efe0-47ee-9dc8-1c68a2ce3e65
名前 / ファイル | ライセンス | アクション |
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ceramics-04-00023.pdf (950.5 kB)
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Item type | 学術雑誌論文 = Journal Article(1) | |||||||||||
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公開日 | 2021-06-08 | |||||||||||
資源タイプ | ||||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
資源タイプ | journal article | |||||||||||
タイトル | ||||||||||||
タイトル | Release Profiles of Dyes and Proteins from Calcium Phosphate Microspheres with Different Crystalline Phases | |||||||||||
その他のタイトル | ||||||||||||
その他のタイトル | Release profiles of dyes and proteins from calcium phosphate microspheres with different crystalline phase | |||||||||||
言語 | ||||||||||||
言語 | eng | |||||||||||
著者 |
宮崎, 敏樹
× 宮崎, 敏樹
WEKO
6369
× Masuda, Koudai× Sakamoto, Kazuki |
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抄録 | ||||||||||||
内容記述タイプ | Abstract | |||||||||||
内容記述 | Calcium phosphate is attracting attention as a bone repair material and a controlled-release carrier of various drugs such as bone disease therapeutic agents and anticancer agents. Compared with some bioabsorbable polymers, calcium phosphates have the advantage of preventing a pH decrease in the surrounding body fluid. However, there are few studies comparing the effect of supporting substances with different physicochemical properties on the production of calcium phosphate microspheres with different crystalline phases. In this study, we investigated conditions for obtaining low crystallinity apatite and octacalcium phosphate (OCP) microspheres from calcium carbonate microspheres with different crystalline structures using a simple phosphoric acid treatment. Furthermore, we investigated the adsorption and release behavior of different dyes and proteins from the apatite and OCP microspheres. Overall, the factors governing the adsorption and release behavior are different depending on the molecular size and surface charge of the dye and protein adsorbates. | |||||||||||
書誌情報 |
Ceramics 巻 4, 号 2, p. 291-301, 発行日 2021-06-06 |
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出版社 | ||||||||||||
出版者 | MDPI | |||||||||||
DOI | ||||||||||||
関連タイプ | isIdenticalTo | |||||||||||
識別子タイプ | DOI | |||||||||||
関連識別子 | https://doi.org/10.3390/ceramics4020023 | |||||||||||
日本十進分類法 | ||||||||||||
主題Scheme | NDC | |||||||||||
主題 | 573 | |||||||||||
ISSN | ||||||||||||
収録物識別子タイプ | ISSN | |||||||||||
収録物識別子 | 2571-6131 | |||||||||||
著作権関連情報 | ||||||||||||
権利情報 | Copyright (c) 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). | |||||||||||
キーワード | ||||||||||||
主題Scheme | Other | |||||||||||
主題 | apatite | |||||||||||
キーワード | ||||||||||||
主題Scheme | Other | |||||||||||
主題 | octacalcium phosphate (OCP) | |||||||||||
キーワード | ||||||||||||
主題Scheme | Other | |||||||||||
主題 | microsphere | |||||||||||
キーワード | ||||||||||||
主題Scheme | Other | |||||||||||
主題 | drug delivery | |||||||||||
キーワード | ||||||||||||
主題Scheme | Other | |||||||||||
主題 | dye | |||||||||||
キーワード | ||||||||||||
主題Scheme | Other | |||||||||||
主題 | protein | |||||||||||
キーワード | ||||||||||||
主題Scheme | Other | |||||||||||
主題 | mesopore | |||||||||||
キーワード | ||||||||||||
主題Scheme | Other | |||||||||||
主題 | surface charge | |||||||||||
出版タイプ | ||||||||||||
出版タイプ | VoR | |||||||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||
査読の有無 | ||||||||||||
値 | yes | |||||||||||
研究者情報 | ||||||||||||
https://hyokadb02.jimu.kyutech.ac.jp/html/323_ja.html | ||||||||||||
論文ID(連携) | ||||||||||||
10364608 | ||||||||||||
連携ID | ||||||||||||
8941 | ||||||||||||
著者別名 | ||||||||||||
姓名 | Miyazaki, Toshiki | |||||||||||
言語 | en | |||||||||||
姓名 | 宮崎, 敏樹 | |||||||||||
言語 | ja | |||||||||||
姓名 | ミヤザキ, トシキ | |||||||||||
言語 | ja-Kana | |||||||||||
著者別名 | ||||||||||||
姓名 | Masuda, K. | |||||||||||
著者別名 | ||||||||||||
姓名 | Sakamoto, K. |