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Preparation of bioactive and antibacterial PMMA-based bone cement by modification with quaternary ammonium and alkoxysilane
http://hdl.handle.net/10228/00008409
http://hdl.handle.net/10228/00008409234972c6-2ac1-4146-a02f-075dc9b975b1
名前 / ファイル | ライセンス | アクション |
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08853282211004413.pdf (2.4 MB)
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Item type | 学術雑誌論文 = Journal Article(1) | |||||||||||||||||
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公開日 | 2021-07-29 | |||||||||||||||||
資源タイプ | ||||||||||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||
資源タイプ | journal article | |||||||||||||||||
タイトル | ||||||||||||||||||
タイトル | Preparation of bioactive and antibacterial PMMA-based bone cement by modification with quaternary ammonium and alkoxysilane | |||||||||||||||||
言語 | ||||||||||||||||||
言語 | eng | |||||||||||||||||
著者 |
Wang, Haiyang
× Wang, Haiyang× 前田, 憲成
WEKO
649
× 宮崎, 敏樹
WEKO
6369
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抄録 | ||||||||||||||||||
内容記述タイプ | Abstract | |||||||||||||||||
内容記述 | Bone cement based on poly(methyl methacrylate) (PMMA) powder and methyl methacrylate (MMA) liquid is a very popular biomaterial used for the fixation of artificial joints. However, there is a risk of this cement loosening from bone because of a lack of bone-bonding bioactivity. Apatite formation in the body environment is a prerequisite for cement bioactivity. Additionally, suppression of infection during implantation is required for bone cements to be successfully introduced into the human body. In this study, we modified PMMA cement with γ-methacryloxypropyltrimetoxysilane and calcium acetate to introduce bioactive properties and 2-(tert-butylamino)ethyl methacrylate (TBAEMA) to provide antibacterial properties. The long-term antibacterial activity is attributed to the copolymerization of TBAEMA and MMA. As the TBAEMA content increased, the setting time increased and the compressive strength decreased. After soaking in simulated body fluid, an apatite layer was detected within 7 days, irrespective of the TBAEMA content. The cement showed better antibacterial activity against Gram-negative E. Coli than Gram-positive bacteria; however, of the Gram-positive bacteria investigated, B. subtilis was more susceptible than S. aureus. | |||||||||||||||||
書誌情報 |
Journal of Biomaterials Applications 巻 36, 号 2, p. 311-320, 発行日 2021-03-24 |
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出版社 | ||||||||||||||||||
出版者 | Sage Publications | |||||||||||||||||
DOI | ||||||||||||||||||
関連タイプ | isVersionOf | |||||||||||||||||
識別子タイプ | DOI | |||||||||||||||||
関連識別子 | https://doi.org/10.1177/08853282211004413 | |||||||||||||||||
日本十進分類法 | ||||||||||||||||||
主題Scheme | NDC | |||||||||||||||||
主題 | 492 | |||||||||||||||||
ISSN | ||||||||||||||||||
収録物識別子タイプ | ISSN | |||||||||||||||||
収録物識別子 | 1530-8022 | |||||||||||||||||
ISSN | ||||||||||||||||||
収録物識別子タイプ | ISSN | |||||||||||||||||
収録物識別子 | 0885-3282 | |||||||||||||||||
著作権関連情報 | ||||||||||||||||||
権利情報 | Haiyang Wang, Toshinari Maeda, Toshiki Miyazaki, Preparation of bioactive and antibacterial PMMA-based bone cement by modification with quaternary ammonium and alkoxysilane, Journal of Biomaterials Applications (vol.36 Issue2) pp. 311-320. Copyright (c) 2021 SAGE Publications. DOI: 10.1177/08853282211004413. | |||||||||||||||||
キーワード | ||||||||||||||||||
主題Scheme | Other | |||||||||||||||||
主題 | PMMA bone cement | |||||||||||||||||
キーワード | ||||||||||||||||||
主題Scheme | Other | |||||||||||||||||
主題 | 2-(tert-butylamino)ethyl methacrylate | |||||||||||||||||
キーワード | ||||||||||||||||||
主題Scheme | Other | |||||||||||||||||
主題 | mechanical property | |||||||||||||||||
キーワード | ||||||||||||||||||
主題Scheme | Other | |||||||||||||||||
主題 | apatite formation | |||||||||||||||||
キーワード | ||||||||||||||||||
主題Scheme | Other | |||||||||||||||||
主題 | antibacterial activity | |||||||||||||||||
出版タイプ | ||||||||||||||||||
出版タイプ | AM | |||||||||||||||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||||||||||||
査読の有無 | ||||||||||||||||||
値 | yes | |||||||||||||||||
研究者情報 | ||||||||||||||||||
https://hyokadb02.jimu.kyutech.ac.jp/html/323_ja.html | ||||||||||||||||||
論文ID(連携) | ||||||||||||||||||
10374493 | ||||||||||||||||||
連携ID | ||||||||||||||||||
9037 | ||||||||||||||||||
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内容記述タイプ | Other | |||||||||||||||||
内容記述 | Journal Article | |||||||||||||||||
著者別名 | ||||||||||||||||||
姓名 | Wang, H. | |||||||||||||||||
著者別名 | ||||||||||||||||||
姓名 | Maeda, Toshinari | |||||||||||||||||
言語 | en | |||||||||||||||||
姓名 | 前田, 憲成 | |||||||||||||||||
言語 | ja | |||||||||||||||||
姓名 | マエダ, トシナリ | |||||||||||||||||
言語 | ja-Kana | |||||||||||||||||
著者別名 | ||||||||||||||||||
姓名 | Miyazaki, Toshiki | |||||||||||||||||
言語 | en | |||||||||||||||||
姓名 | 宮崎, 敏樹 | |||||||||||||||||
言語 | ja | |||||||||||||||||
姓名 | ミヤザキ, トシキ | |||||||||||||||||
言語 | ja-Kana | |||||||||||||||||
著者所属 | ||||||||||||||||||
Kyushu Institute of Technology | ||||||||||||||||||
著者所属 | ||||||||||||||||||
Kyushu Institute of Technology | ||||||||||||||||||
著者所属 | ||||||||||||||||||
Kyushu Institute of Technology |