Kyushu Institute of Technology Academic Repository
Kyutacarは九州工業大学で生産された研究成果を オープンアクセスで提供する機関リポジトリシステムです。 Kyutacar is open-access repository of research by members of the Kyushu Institute of Technology.
Kyushu Institute of Technology
Kyushu Institute of Technology
Kyushu Institute of Technology
抄録
Calcium phosphate is attracting attention as a bone repair material and a controlled-release carrier of various drugs such as bone disease therapeutic agents and anticancer agents. Compared with some bioabsorbable polymers, calcium phosphates have the advantage of preventing a pH decrease in the surrounding body fluid. However, there are few studies comparing the effect of supporting substances with different physicochemical properties on the production of calcium phosphate microspheres with different crystalline phases. In this study, we investigated conditions for obtaining low crystallinity apatite and octacalcium phosphate (OCP) microspheres from calcium carbonate microspheres with different crystalline structures using a simple phosphoric acid treatment. Furthermore, we investigated the adsorption and release behavior of different dyes and proteins from the apatite and OCP microspheres. Overall, the factors governing the adsorption and release behavior are different depending on the molecular size and surface charge of the dye and protein adsorbates.
雑誌名
Ceramics
巻
4
号
2
ページ
291 - 301
発行年
2021-06-06
出版者
MDPI
ISSN
2571-6131
DOI
https://doi.org/10.3390/ceramics4020023
権利
Copyright (c) 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/).
日本十進分類法
573
その他のタイトル
Release profiles of dyes and proteins from calcium phosphate microspheres with different crystalline phase
Release Profiles of Dyes and Proteins from Calcium Phosphate Microspheres with Different Crystalline Phases
ceramics-04-00023.pdf
(950.55KB)
