| アイテムタイプ |
学術雑誌論文 = Journal Article(1) |
| 公開日 |
2024-04-11 |
| 資源タイプ |
|
|
資源タイプ識別子 |
http://purl.org/coar/resource_type/c_6501 |
|
資源タイプ |
journal article |
| タイトル |
|
|
タイトル |
Fabrication of quantum dot-immobilized Y2O3 microspheres with effective photoluminescence for cancer radioembolization therapy |
|
言語 |
en |
| 言語 |
|
|
言語 |
eng |
| 著者 |
宮崎, 敏樹
Wakayama, Takumi
Oda, Masaru
Kawashita, Masakazu
|
| 抄録 |
|
|
内容記述タイプ |
Abstract |
|
内容記述 |
Microspheres composed of Y-containing materials are effective agents for cancer radioembolization therapy using β-rays. The distribution and dynamics of these microspheres in tissues can be easily determined by providing the microspheres with an imaging function. In addition, the use of quantum dots will enable the detection of microspheres at the individual particle level with high sensitivity. In this study, core – shell quantum dots were bound to chemically modified yttria microspheres under various conditions, and the effect of reaction conditions on the photoluminescence properties of the microspheres was investigated. The quantum dots were immobilized on the surfaces of the microspheres through dehydration – condensation reactions between the carboxy groups of quantum dots and the amino groups of silane-treated microspheres. As the reaction time increased, the photoluminescence peak blue shifted, and the photoluminescence intensity and lifetime decreased. Therefore, a moderate period of the immobilization process was optimal for imparting effective photoluminescence properties. This study is expected to facilitate particle-level tracking of microsphere dynamics in biological tissues for the development of minimally invasive cancer radiotherapy of deep-seated tumors. |
|
言語 |
en |
| 書誌情報 |
en : Science and Technology of Advanced Materials
巻 25,
号 1,
p. 2331412,
発行日 2024-04-02
|
| 出版社 |
|
|
出版者 |
Taylor & Francis |
|
言語 |
en |
| DOI |
|
|
関連タイプ |
isIdenticalTo |
|
|
識別子タイプ |
DOI |
|
|
関連識別子 |
https://doi.org/10.1080/14686996.2024.2331412 |
| ISSN |
|
|
収録物識別子タイプ |
PISSN |
|
収録物識別子 |
1468-6996 |
| ISSN |
|
|
収録物識別子タイプ |
EISSN |
|
収録物識別子 |
1878-5514 |
| 著作権関連情報 |
|
|
権利情報Resource |
http://creativecommons.org/licenses/by-nc/4.0/ |
|
権利情報 |
Copyright (c) 2024 The Author(s). Published by National Institute for Materials Science in partnership with Taylor & Francis Group. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License, which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent. |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
Y2O3 microsphere |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
water-in-oil emulsion |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
quantum dot |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
chemical immobilization |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
photoluminescence |
| キーワード |
|
|
主題Scheme |
Other |
|
主題 |
concentration quenching |
| 出版タイプ |
|
|
出版タイプ |
VoR |
|
出版タイプResource |
http://purl.org/coar/version/c_970fb48d4fbd8a85 |
| 査読の有無 |
|
|
値 |
yes |
| 研究者情報 |
|
|
URL |
https://hyokadb02.jimu.kyutech.ac.jp/html/323_ja.html |
| 論文ID（連携） |
|
|
値 |
10429456 |
| 連携ID |
|
|
値 |
11963 |
10429456.pdf (2.9 MB)
