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アイテム
Apatite Deposition on Hyaluronic Acid Gels in Biomimetic Conditions
http://hdl.handle.net/10228/4610
http://hdl.handle.net/10228/4610f36ea8df-9d78-48c6-8da4-04c7588d96ef
| 名前 / ファイル | ライセンス | アクション |
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article_1.pdf (515.3 kB)
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| アイテムタイプ | 学術雑誌論文 = Journal Article(1) | |||||||||||||
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| 公開日 | 2010-05-21 | |||||||||||||
| 資源タイプ | ||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||
| 資源タイプ | journal article | |||||||||||||
| タイトル | ||||||||||||||
| タイトル | Apatite Deposition on Hyaluronic Acid Gels in Biomimetic Conditions | |||||||||||||
| 言語 | en | |||||||||||||
| 言語 | ||||||||||||||
| 言語 | eng | |||||||||||||
| 著者 |
Morita, Yumi
× Morita, Yumi× Matsumoto, Chie× 宮崎, 敏樹
WEKO
6369
× Ishida, Eiichi× Tanaka, Kenkoh× Goto, Tetsuya |
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| 抄録 | ||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||
| 内容記述 | Bioactive ceramics are used for bone-repairing owing to attractive features such as direct bone-bonding in living body, because they have the ability to bond directly to bone. However, there is limitation on clinical applications due to their inappropriate mechanical properties performances such as higher brittleness and lower fracture toughness than natural bone. Organic-inorganic hybrids consisting of organic polymer and the apatite would be attractive as novel bioactive bone substitutes with mechanical performances analogous to those of natural bone. We attempted preparation of apatite-polymer hybrids from hyaluronic acid. It has been attractive for bone- and cartilage-repairing materials due to high biological compatibility. The hydroxyl groups in side chains of the hyaluronic acid were bridged by divinylsulfone. Dense films were obtained after drying at ambient pressure, whereas porous specimens were formed by freeze-drying. They were treated with 1 M-CaCI2 aqueous solution for 24 h. Ability of apatite formation on the specimens was examined in vitro using simulated body fluid (SBF, Kokubo solution). The specimens formed the apatite in SBF within 7 d, when they were previously treated with CaCb solution. | |||||||||||||
| 言語 | en | |||||||||||||
| 書誌情報 |
en : Transactions of the Materials Research Society of Japan 巻 34, 号 1, p. 85-87, 発行日 2009-04-01 |
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| 出版社 | ||||||||||||||
| 出版者 | 日本MRS | |||||||||||||
| 言語 | ja | |||||||||||||
| DOI | ||||||||||||||
| 関連タイプ | isIdenticalTo | |||||||||||||
| 識別子タイプ | DOI | |||||||||||||
| 関連識別子 | https://doi.org/10.14723/tmrsj.34.85 | |||||||||||||
| ISSN | ||||||||||||||
| 収録物識別子タイプ | PISSN | |||||||||||||
| 収録物識別子 | 1382-3469 | |||||||||||||
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| 収録物識別子タイプ | EISSN | |||||||||||||
| 収録物識別子 | 2188-1650 | |||||||||||||
| 著作権関連情報 | ||||||||||||||
| 権利情報 | 著作権は日本ＭＲＳに帰属します。 | |||||||||||||
| キーワード | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | Hyaluronic acid | |||||||||||||
| キーワード | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | Organic-inorganic hybrids | |||||||||||||
| キーワード | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | SBF | |||||||||||||
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| 主題Scheme | Other | |||||||||||||
| 主題 | Apatite | |||||||||||||
| キーワード | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | Biomimetic process | |||||||||||||
| キーワード | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | Bioactivity | |||||||||||||
| 出版タイプ | ||||||||||||||
| 出版タイプ | VoR | |||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||
| 査読の有無 | ||||||||||||||
| 値 | yes | |||||||||||||
| 業績ID | ||||||||||||||
| 値 | FAD3066ED932FBFE49257688003A90DF | |||||||||||||
