@article{oai:kyutech.repo.nii.ac.jp:00004324,
 author = {Liu, Chao and Matsunami, Chisato and Shirosaki, Yuki and 城崎, 由紀 and Miyazaki, Toshiki and 宮崎, 敏樹},
 issue = {5},
 journal = {Dental Materials Journal},
 month = {Oct},
 note = {Cobalt-chromium (Co-Cr) alloys are used in clinical practice for the hard tissue reconstruction because of their favorable biocompatibility and mechanical properties. However, their applications have been limited because of their poor bioactivity, making them poor at bone-bonding. In this study, the bioactivity of a Co-Cr alloy was evaluated following the immobilization of cross-linked poly-γ-glutamic acid (γ-PGA) onto its surface via the formation of 11-aminoundecylphosphonic acid self-assembled monolayers (SAMs). Results of X-ray photoelectron spectroscopy revealed the presence of a new P2p peak, which confirms SAMs formation. Furthermore, the surface became highly hydrophobic following the immobilization with γ-PGA. Subsequent treatment with CaCl2 at 0.5 M or more and soaking in a simulated body fluid led to the formation of a low crystalline apatite. The present results show that chemical modification can be used to induce the formation of an apatite layer on the surface of a Co-Cr alloy in simulated body fluid.},
 pages = {707--712},
 title = {Bioactive Co-Cr Alloy for Biomedical Applications Prepared by Surface Modification Using Self-assembled Monolayers and Poly-γ-glutamic Acid},
 volume = {34},
 year = {2015},
 yomi = {シロサキ, ユキ and ミヤザキ, トシキ}
}