WEKO3
アイテム
Effect of cra Gene Mutation on the Metabolism of Escherichia Coli for a Mixture of Multiple Carbon Sources
http://hdl.handle.net/10228/5567
http://hdl.handle.net/10228/5567e5edabd7-3639-497e-985b-ca7b3576d69e
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
ABB_2013032910462143.pdf (396.4 kB)
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| アイテムタイプ | 学術雑誌論文 = Journal Article(1) | |||||||||||||
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| 公開日 | 2016-02-03 | |||||||||||||
| 資源タイプ | ||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||
| 資源タイプ | journal article | |||||||||||||
| タイトル | ||||||||||||||
| タイトル | Effect of cra Gene Mutation on the Metabolism of Escherichia Coli for a Mixture of Multiple Carbon Sources | |||||||||||||
| 言語 | ||||||||||||||
| 言語 | eng | |||||||||||||
| 著者 |
Yao, Ruilian
× Yao, Ruilian× 倉田, 博之
WEKO
2130
× Shimizu, Kazuyuki |
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| 抄録 | ||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||
| 内容記述 | The major player for catabolite repression is the phosphotransferase systems (PTSs) and cAMP-Crp. Moreover, Cra controls the carbon flow in the metabolic network. In the present research, the effect of modulating cra gene (Δcra) on the consumption of multiple carbon sources such as glucose and fructose (as well as xylose) was investigated under both aerobic and anaerobic conditions. It was shown that glucose and fructose could be co-metabolized with fructose consumed faster than glucose in cra mutant under both aerobic and anaerobic conditions. It was also implied that cra mutant consumed higher amount of total carbon sources, which contributed to the highest metabolite production as compared to the wild type strain. Thus, cra mutant can be a good candidate for the efficient utilization of multiple carbon sources such as glucose and fructose, where xylose consumption was repressed by catabolite repression. The overall regulation mechanisms were clarified based on fermentation data and gene transcript analysis. | |||||||||||||
| 書誌情報 |
Advances in Bioscience and Biotechnology 巻 4, 号 3, p. 477-486, 発行日 2013-03 |
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| 出版社 | ||||||||||||||
| 出版者 | Scientific Research Publishing | |||||||||||||
| DOI | ||||||||||||||
| 関連タイプ | isIdenticalTo | |||||||||||||
| 識別子タイプ | DOI | |||||||||||||
| 関連識別子 | info:doi/10.4236/abb.2013.43A063 | |||||||||||||
| 著作権関連情報 | ||||||||||||||
| 権利情報 | Scientific Research Publishing | |||||||||||||
| キーワード | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | Escherichia coli | |||||||||||||
| キーワード | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | cra Mutant | |||||||||||||
| キーワード | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | Catabolite Regulation | |||||||||||||
| 出版タイプ | ||||||||||||||
| 出版タイプ | VoR | |||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||
| 査読の有無 | ||||||||||||||
| 値 | yes | |||||||||||||
| 研究者情報 | ||||||||||||||
| URL | https://hyokadb02.jimu.kyutech.ac.jp/html/265_ja.html | |||||||||||||
| 連携ID | ||||||||||||||
| 値 | 5318 | |||||||||||||
