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Design of novel bioactive materials through organic modification of calcium silicate
http://hdl.handle.net/10228/6029
http://hdl.handle.net/10228/602919f80f9c-efaa-4e9d-9e7d-139da8af37c7
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
JECS27_1527.pdf (1.2 MB)
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| Item type | 学術雑誌論文 = Journal Article(1) | |||||||||||||
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| 公開日 | 2017-02-15 | |||||||||||||
| 資源タイプ | ||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||
| 資源タイプ | journal article | |||||||||||||
| タイトル | ||||||||||||||
| タイトル | Design of novel bioactive materials through organic modification of calcium silicate | |||||||||||||
| 言語 | en | |||||||||||||
| 言語 | ||||||||||||||
| 言語 | eng | |||||||||||||
| 著者 |
Ohtsuki, Chikara
× Ohtsuki, Chikara× 宮崎, 敏樹
WEKO
6369
× Kamitakahara, Masanobu× Tanihara, Masao |
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| 抄録 | ||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||
| 内容記述 | Bioactive ceramics have attractive feature for bone repair such as direct bone-bonding in the body. However their clinical application is limited to low loaded portions due to their inappropriate mechanical performances such as higher brittleness and lower flexibility than natural bone. The essential condition for artificial materials to show bioactivity is formation of bone-like apatite on their surfaces in body environment. This apatite formation is triggered by silanol (Si–OH) group on the material surfaces and release of Ca2+. These findings bring us an idea that novel bioactive materials with high flexibility can be designed by organic modification of calcium silicate. We synthesized organic–inorganic hybrids from organic polymers including 2-hydroxyethylmethacrylate (HEMA), starch and alginate by modification with alkoxysilane and calcium chloride. The hybrids formed apatite on their surfaces in simulated body fluid (SBF, Kokubo solution). Such a modification was also effective for providing conventional polymethylmethacrylate (PMMA)-based bone cement with bioactivity. | |||||||||||||
| 備考 | ||||||||||||||
| 内容記述タイプ | Other | |||||||||||||
| 内容記述 | IX Conference and Exhibition of the European Ceramic Society: June 19-23, 2005, Portorož, Slovenia | |||||||||||||
| 書誌情報 |
Journal of the European Ceramic Society 巻 27, 号 2-3, p. 1527-1533, 発行日 2007-04-01 |
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| 出版社 | ||||||||||||||
| 出版者 | Elsevier | |||||||||||||
| DOI | ||||||||||||||
| 関連タイプ | isVersionOf | |||||||||||||
| 識別子タイプ | DOI | |||||||||||||
| 関連識別子 | https://doi.org/10.1016/j.jeurceramsoc.2006.04.018 | |||||||||||||
| NCID | ||||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||||
| 収録物識別子 | AA11537849 | |||||||||||||
| ISSN | ||||||||||||||
| 収録物識別子タイプ | PISSN | |||||||||||||
| 収録物識別子 | 0928-4931 | |||||||||||||
| 著作権関連情報 | ||||||||||||||
| 権利情報 | Copyright (c) 2006 Elsevier Ltd. | |||||||||||||
| キーワード | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | Nanocomposites | |||||||||||||
| キーワード | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | Apatite | |||||||||||||
| キーワード | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | Silicate | |||||||||||||
| キーワード | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | Biomedical applications | |||||||||||||
| キーワード | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | Bioactivity | |||||||||||||
| 出版タイプ | ||||||||||||||
| 出版タイプ | AM | |||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||||||||
| 査読の有無 | ||||||||||||||
| 値 | yes | |||||||||||||
| 研究者情報 | ||||||||||||||
| URL | https://hyokadb02.jimu.kyutech.ac.jp/html/323_ja.html | |||||||||||||
| 連携ID | ||||||||||||||
| 値 | 4493 | |||||||||||||
