{"created":"2023-05-15T11:58:53.165880+00:00","id":5082,"links":{},"metadata":{"_buckets":{"deposit":"982a526f-d566-4095-84d4-0da4d6ad91f2"},"_deposit":{"created_by":3,"id":"5082","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"5082"},"status":"published"},"_oai":{"id":"oai:kyutech.repo.nii.ac.jp:00005082","sets":["8:9"]},"author_link":["20466","20467","20468","6369","20470","20471"],"control_number":"5082","item_21_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2016-08-10","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageStart":"045006","bibliographicVolumeNumber":"11","bibliographic_titles":[{"bibliographic_title":"Biomedical Materials","bibliographic_titleLang":"en"}]}]},"item_21_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"The osteoconductivity mechanism of hydroxyapatite (HAp) has not been elucidated. It is hypothesized that specific proteins adsorb on HAp, promoting its osteoconductivity. To verify this hypothesis, we compared the adsorption behavior of fibronectin (Fn) on HAp powder and on α-alumina (α-Al2O3) powder, a material with no osteoconductivity. More Fn adsorbed on α-Al2O3 than on HAp, irrespective of the Fn concentration, and there was no significant difference in the secondary structure of Fn adsorbed on HAp and α-Al2O3. Further, it is possible that Fn did not adsorb on HAp and α-Al2O3 through the Arg-Gry-Asp motif of Fn. The amount of Fn adsorbed on HAp oriented to the a(b)-axis with very little decrease in carbonate and the adsorbed Fn had a smaller α-helix structure content. The results suggest that the secondary and/or higher-order structure rather than the amount of adsorbed Fn might affect the osteoconductivity of HAp, which might be electrostatically controlled by the crystal face orientation and/or carbonate content of HAp, although this should be confirmed by a cell culture test in the future.","subitem_description_language":"en","subitem_description_type":"Abstract"}]},"item_21_link_62":{"attribute_name":"研究者情報","attribute_value_mlt":[{"subitem_link_url":"https://hyokadb02.jimu.kyutech.ac.jp/html/323_ja.html"}]},"item_21_publisher_7":{"attribute_name":"出版社","attribute_value_mlt":[{"subitem_publisher":"IOP Publishing","subitem_publisher_language":"en"}]},"item_21_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1088/1748-6041/11/4/045006","subitem_relation_type_select":"DOI"}}]},"item_21_rights_13":{"attribute_name":"著作権関連情報","attribute_value_mlt":[{"subitem_rights":"IOP Publishing. This is an author-created, un-copyedited version of an article accepted for publication/published in Biomedical materials. IOP Publishing Ltd is not responsible for any errors or omissions in this version of the manuscript or any version derived from it. The Version of Record is available online at  http://dx.doi.org/10.1088/1748-6041/11/4/045006."}]},"item_21_select_59":{"attribute_name":"査読の有無","attribute_value_mlt":[{"subitem_select_item":"yes"}]},"item_21_source_id_8":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1748-605X","subitem_source_identifier_type":"EISSN"},{"subitem_source_identifier":"1748-6041","subitem_source_identifier_type":"PISSN"}]},"item_21_text_28":{"attribute_name":"論文ID（連携）","attribute_value_mlt":[{"subitem_text_value":"10297006"}]},"item_21_text_63":{"attribute_name":"連携ID","attribute_value_mlt":[{"subitem_text_value":"5511"}]},"item_21_version_type_58":{"attribute_name":"出版タイプ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Hasegawa, Maki","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kudo, Tada-aki","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kanetaka, Hiroyasu","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorAffiliations":[{"affiliationNames":[{}]}],"creatorNames":[{"creatorName":"Miyazaki, Toshiki","creatorNameLang":"en"},{"creatorName":"宮崎, 敏樹","creatorNameLang":"ja"},{"creatorName":"ミヤザキ, トシキ","creatorNameLang":"ja-Kana"}],"familyNames":[{},{},{}],"givenNames":[{},{},{}],"nameIdentifiers":[{},{},{},{},{}]},{"creatorNames":[{"creatorName":"Hashimoto, Masami","creatorNameLang":"en"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Kawashita, Masakazu","creatorNameLang":"en"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2017-08-21"}],"displaytype":"detail","filename":"BM11_045006.pdf","filesize":[{"value":"602.1 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"BM11_045006.pdf","url":"https://kyutech.repo.nii.ac.jp/record/5082/files/BM11_045006.pdf"},"version_id":"e4959c12-e30a-43a9-bdf3-7bd03922796a"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"adsorption","subitem_subject_scheme":"Other"},{"subitem_subject":"fibronectin","subitem_subject_scheme":"Other"},{"subitem_subject":"hydroxyapatite","subitem_subject_scheme":"Other"},{"subitem_subject":"α-alumina","subitem_subject_scheme":"Other"},{"subitem_subject":"osteoconductivity","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Fibronectin Adsorption on Osteoconductive Hydroxyapatite and Non-osteoconductive α-alumina","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Fibronectin Adsorption on Osteoconductive Hydroxyapatite and Non-osteoconductive α-alumina","subitem_title_language":"en"}]},"item_type_id":"21","owner":"3","path":["9"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2017-08-21"},"publish_date":"2017-08-21","publish_status":"0","recid":"5082","relation_version_is_last":true,"title":["Fibronectin Adsorption on Osteoconductive Hydroxyapatite and Non-osteoconductive α-alumina"],"weko_creator_id":"3","weko_shared_id":-1},"updated":"2024-04-02T08:38:13.721383+00:00"}