{"created":"2023-05-15T11:59:02.295528+00:00","id":5298,"links":{},"metadata":{"_buckets":{"deposit":"4c8eb823-0d2b-4ba3-b9bc-e37ce5ec82d1"},"_deposit":{"created_by":3,"id":"5298","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"5298"},"status":"published"},"_oai":{"id":"oai:kyutech.repo.nii.ac.jp:00005298","sets":["8:24"]},"author_link":["21355","21342","21341","21325"],"item_21_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2000-02-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"445","bibliographicPageStart":"439","bibliographicVolumeNumber":"73","bibliographic_titles":[{"bibliographic_title":"Bulletin of the Chemical Society of Japan"}]}]},"item_21_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Amphiphilic 21-peptides with six and nine L-2-(2,2,2-trifluoroethyl)glycines as the hydrophobic amino acids and lysine and glutamic acid as the hydrophilic amino acids were synthesized. The CD spectra showed that these peptides with　L-2-(2,2,2-trifluoroethyl)glycines took a random conformation in H2O. On the contrary, similar amphiphilic 21-peptides with leucine as the hydrophobic amino acids took a helical conformation in H2O. The peptides with L-2-(2,2,2-trifluoroethyl)glycines took a helical conformation in H2O containing a > 20% volume of 2,2,2-trifluoroethanol. These facts suggested the hydrophobic nature of the L-trifluoroethylglycines. The peptide with six L-2-(2,2,2-trifluoroethyl)glycines took a helical structure in methanol, however it slowly changed into the β-structure within 24 h. Interestingly, the peptide with nine L-2-(2,2,2-trifluoroethyl)glycines formed a stable helix under the same conditions. The peptide with nine L-2-(2,2,2-trifluoroethyl)glycines preferred a helical structure, probably because the assembling of the Tfeg side chains was more effective in forming its helix rather than the β-structure.","subitem_description_type":"Abstract"}]},"item_21_description_60":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Journal Article","subitem_description_type":"Other"}]},"item_21_link_62":{"attribute_name":"研究者情報","attribute_value_mlt":[{"subitem_link_url":"https://hyokadb02.jimu.kyutech.ac.jp/html/114_ja.html"}]},"item_21_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"公益社団法人日本化学会"}]},"item_21_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1246/bcsj.73.439","subitem_relation_type_select":"DOI"}}]},"item_21_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"公益社団法人日本化学会"}]},"item_21_select_59":{"attribute_name":"査読の有無","attribute_value_mlt":[{"subitem_select_item":"yes"}]},"item_21_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA00580132","subitem_source_identifier_type":"NCID"}]},"item_21_source_id_8":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1348-0634","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"0009-2673","subitem_source_identifier_type":"ISSN"}]},"item_21_text_28":{"attribute_name":"論文ID（連携）","attribute_value_mlt":[{"subitem_text_value":"10020558"}]},"item_21_text_36":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Department of Applied Chemistry, Faculty of Engineering, Kyushu Institute of Technology"},{"subitem_text_value":"Department of Applied Chemistry, Faculty of Engineering, Kyushu Institute of Technology"},{"subitem_text_value":"Department of Applied Chemistry, Faculty of Engineering, Kyushu Institute of Technology"},{"subitem_text_value":"Institute for Fundamental Research of Organic Chemistry, Kyushu University"}]},"item_21_text_63":{"attribute_name":"連携ID","attribute_value_mlt":[{"subitem_text_value":"276"}]},"item_21_version_type_58":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Arai,  Toru"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Imachi,  Takashi"}],"nameIdentifiers":[{}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[],"affiliationNames":[{"affiliationName":""}]}],"creatorNames":[{"creatorName":"Kato, Tamaki","creatorNameLang":"en"},{"creatorName":"加藤, 珠樹","creatorNameLang":"ja"},{"creatorName":"カトウ, タマキ","creatorNameLang":"ja-Kana"}],"familyNames":[{},{},{}],"givenNames":[{},{},{}],"nameIdentifiers":[{},{},{}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[],"affiliationNames":[{"affiliationName":""}]}],"creatorNames":[{"creatorName":"Nishino, Norikazu","creatorNameLang":"en"},{"creatorName":"西野, 憲和","creatorNameLang":"ja"},{"creatorName":"ニシノ, ノリカズ","creatorNameLang":"ja-Kana"}],"familyNames":[{},{},{}],"givenNames":[{},{},{}],"nameIdentifiers":[{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-01-19"}],"displaytype":"detail","filename":"BCSJ73_439.pdf","filesize":[{"value":"2.8 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"BCSJ73_439.pdf","url":"https://kyutech.repo.nii.ac.jp/record/5298/files/BCSJ73_439.pdf"},"version_id":"e2f88888-c4e0-4f11-8624-377db2e8b949"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"The Conformation of de Novo Designed Amphiphilic Peptides with Six or Nine L-2-(2,2,2-Trifluoroethyl)glycines as the Hydrophobic Amino Acid","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"The Conformation of de Novo Designed Amphiphilic Peptides with Six or Nine L-2-(2,2,2-Trifluoroethyl)glycines as the Hydrophobic Amino Acid"}]},"item_type_id":"21","owner":"3","path":["24"],"pubdate":{"attribute_name":"公開日","attribute_value":"2018-01-19"},"publish_date":"2018-01-19","publish_status":"0","recid":"5298","relation_version_is_last":true,"title":["The Conformation of de Novo Designed Amphiphilic Peptides with Six or Nine L-2-(2,2,2-Trifluoroethyl)glycines as the Hydrophobic Amino Acid"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-10-26T01:30:52.726233+00:00"}