@article{oai:kyutech.repo.nii.ac.jp:00005678,
 author = {Miyazaki, Toshiki and 宮崎, 敏樹 and Matsunami,  Chisato and Shirosaki, Yuki and 城崎, 由紀},
 issue = {2},
 journal = {Materials Science and Engineering: C},
 month = {Aug},
 note = {Polyetheretherketone (PEEK) has attracted much attention as an artificial intervertebral spacer for spinal reconstruction. Furthermore, PEEK plastic reinforced with carbon fiber has twice the bending strength of pure PEEK. However, the PEEK-based materials do not show ability for direct bone bonding, i.e., bioactivity. Although several trials have been conducted for enabling PEEK with bioactivity, few studies have reported on bioactive surface modification of carbon–PEEK composites. In the present study, we attempted the preparation of bioactive carbon-PEEK composites by chemical treatments with H2SO4 and CaCl2. Bioactivity was evaluated by in vitro apatite formation in simulated body fluid (SBF). The apatite formation on the carbon–PEEK composite was compared with that of pure PEEK. Both pure PEEK and carbon-PEEK composite formed the apatite in SBF when they were treated with H2SO4 and CaCl2; the latter showed higher apatite-forming ability than the former. It is conjectured that many functional groups able to induce the apatite nucleation, such as sulfo and carboxyl groups, are incorporated into the dispersed carbon phase in the carbon–PEEK composites.},
 pages = {71--75},
 title = {Bioactive Carbon-PEEK Composites Prepared by Chemical Surface Treatment},
 volume = {70},
 year = {2016},
 yomi = {ミヤザキ, トシキ and シロサキ, ユキ}
}