{"created":"2023-05-15T11:59:23.374169+00:00","id":5779,"links":{},"metadata":{"_buckets":{"deposit":"554e2389-d22a-4c6b-b750-fb9ff10a5cc3"},"_deposit":{"created_by":3,"id":"5779","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"5779"},"status":"published"},"_oai":{"id":"oai:kyutech.repo.nii.ac.jp:00005779","sets":["15:20"]},"author_link":["443","23512","23513","446"],"control_number":"5779","item_23_alternative_title_18":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Ambient temperature drying of therapeutic protein solution with use of microwave","subitem_alternative_title_language":"en"}]},"item_23_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2018-09-11","bibliographicIssueDateType":"Issued"},"bibliographic_titles":[{"bibliographic_title":"Proceedings of IDS 2018: 21st International Drying Symposium"}]}]},"item_23_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"High quality drying of therapeutic protein-solution is important in medical and pharmaceutical processing. Freeze-drying is mostly used, but it takes a long drying-time and causes damages of protein structures. In order to improve the drying quality, we propose a microwave vacuum drying performed at ambient temperatures under low-pressure conditions. We are focusing on the Parma-Zyme method for the evaporative drying of protein solutions such as egg white or lysozyme with vitrification. Circular dichroism (CD) spectroscopy is used to detect protein conformation changes due to the drying, and it is found that the ambient temperature drying can preserve the protein conformation.","subitem_description_type":"Abstract"}]},"item_23_description_5":{"attribute_name":"備考","attribute_value_mlt":[{"subitem_description":"21st International Drying Symposium(IDS’2018), 11-14 September 2018, València, Spain","subitem_description_type":"Other"}]},"item_23_link_61":{"attribute_name":"研究者情報","attribute_value_mlt":[{"subitem_link_text":"https://hyokadb02.jimu.kyutech.ac.jp/html/9_ja.html","subitem_link_url":"https://hyokadb02.jimu.kyutech.ac.jp/html/9_ja.html"}]},"item_23_publisher_7":{"attribute_name":"出版社","attribute_value_mlt":[{"subitem_publisher":"IDS 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タカハル","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"Tsuruta","familyNameLang":"en"},{"familyName":"鶴田","familyNameLang":"ja"},{"familyName":"ツルタ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Takaharu","givenNameLang":"en"},{"givenName":"隆治","givenNameLang":"ja"},{"givenName":"タカハル","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"443","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"30172068","nameIdentifierScheme":"e-Rad_Researcher","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/nrid/1000030172068"},{"nameIdentifier":"55633614000","nameIdentifierScheme":"Scopus著者ID","nameIdentifierURI":"https://www.scopus.com/authid/detail.uri?authorId=55633614000"}]},{"creatorNames":[{"creatorName":"Ogawa, T.","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"23512","nameIdentifierScheme":"WEKO"}]},{"creatorNames":[{"creatorName":"Abe, R.","creatorNameLang":"en"}],"nameIdentifiers":[{"nameIdentifier":"23513","nameIdentifierScheme":"WEKO"}]},{"creatorAffiliations":[{"affiliationNames":[{"affiliationNameLang":"ja"}]}],"creatorNames":[{"creatorName":"Tanigawa, Hirofumi","creatorNameLang":"en"},{"creatorName":"谷川, 洋文","creatorNameLang":"ja"},{"creatorName":"タニガワ, ヒロフミ","creatorNameLang":"ja-Kana"}],"familyNames":[{"familyName":"Tanigawa","familyNameLang":"en"},{"familyName":"谷川","familyNameLang":"ja"},{"familyName":"タニガワ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Hirofumi","givenNameLang":"en"},{"givenName":"洋文","givenNameLang":"ja"},{"givenName":"ヒロフミ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"446","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"80197524","nameIdentifierScheme":"e-Rad_Researcher","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/nrid/1000080197524"},{"nameIdentifier":"7005337080","nameIdentifierScheme":"Scopus著者ID","nameIdentifierURI":"https://www.scopus.com/authid/detail.uri?authorId=7005337080"},{"nameIdentifier":"30","nameIdentifierScheme":"九工大研究者情報","nameIdentifierURI":"https://hyokadb02.jimu.kyutech.ac.jp/html/30_ja.html"}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2018-12-03"}],"displaytype":"detail","filename":"10332233.pdf","filesize":[{"value":"1.2 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"10332233.pdf","url":"https://kyutech.repo.nii.ac.jp/record/5779/files/10332233.pdf"},"version_id":"6d4f7d49-990c-481d-a510-98f2f3035cfd"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Microwave vacuum drying","subitem_subject_scheme":"Other"},{"subitem_subject":"Freeze-drying","subitem_subject_scheme":"Other"},{"subitem_subject":"Therapeutic protein","subitem_subject_scheme":"Other"},{"subitem_subject":"Egg white","subitem_subject_scheme":"Other"},{"subitem_subject":"Lysozyme","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"conference paper","resourceuri":"http://purl.org/coar/resource_type/c_5794"}]},"item_title":"Ambient Temperature Drying of Therapeutic Protein Solution with Use of Microwave","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Ambient Temperature Drying of Therapeutic Protein Solution with Use of Microwave","subitem_title_language":"en"}]},"item_type_id":"23","owner":"3","path":["20"],"pubdate":{"attribute_name":"PubDate","attribute_value":"2018-12-03"},"publish_date":"2018-12-03","publish_status":"0","recid":"5779","relation_version_is_last":true,"title":["Ambient Temperature Drying of Therapeutic Protein Solution with Use of Microwave"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2025-06-10T00:17:21.491291+00:00"}