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Numerical Simulation of Skin Formation: The Relationship between Transepidermal Water Loss and Corneum Thickness
http://hdl.handle.net/10228/00007064
http://hdl.handle.net/10228/0000706467bf3419-7955-42f9-b11c-2d75ffca3475
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
10334748.pdf (481.9 kB)
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| アイテムタイプ | 会議発表論文 = Conference Paper(1) | |||||||||||
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| 公開日 | 2019-03-11 | |||||||||||
| 資源タイプ | ||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_5794 | |||||||||||
| 資源タイプ | conference paper | |||||||||||
| タイトル | ||||||||||||
| タイトル | Numerical Simulation of Skin Formation: The Relationship between Transepidermal Water Loss and Corneum Thickness | |||||||||||
| 言語 | en | |||||||||||
| 言語 | ||||||||||||
| 言語 | eng | |||||||||||
| 著者 |
永山, 勝也
× 永山, 勝也
WEKO
17054
× Kurihara, Takeshi |
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| 抄録 | ||||||||||||
| 内容記述タイプ | Abstract | |||||||||||
| 内容記述 | Skin moisturizing has drawn attention in terms of beauty and anti-aging industries. However, it is difficult to observe the inside of the epidermis and the relationship between the epidermis and water content is not yet clear. Computational simulations can be useful in understanding such mechanisms of skin formation. A particle model was used to simulate three-dimensional skin turnover, and the results reproduced the epidermal skin turnover phenomenon. In this study, a diffusion model is introduced into this simulation model and a moisture diffusion analysis of the epidermis was performed. In particular, transepidermal water loss (TEWL) was modeled by considering diffusion and surface evaporation in the stratum corneum and other layers. The relationship between the moisture content and the keratin detachment was considered, and the exfoliation condition of keratin based on the moisture content was calculated in the model. As a result, it was possible to calculate the intraepidermal water content distribution in the skin using the particle model. It was also possible to reproduce phenomena such as keratin thickening due to increase of TEWL. This phenomenon is consistent with cases of dry skin. In the future, it will be necessary to introduce a change in TEWL according to the thickness of the stratum corneum and the diffusion coefficient. | |||||||||||
| 言語 | en | |||||||||||
| 備考 | ||||||||||||
| 内容記述タイプ | Other | |||||||||||
| 内容記述 | 8th Conference on Computational Mechanics (CCM 2018), August 21-23, 2018, Kunming, China. | |||||||||||
| 言語 | en | |||||||||||
| 書誌情報 |
en : Journal of Applied Mathematics and Physics 巻 6, 号 8, p. 1757-1762, 発行日 2018-08-23 |
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| 出版社 | ||||||||||||
| 出版社 | Scientific Research Publishing | |||||||||||
| DOI | ||||||||||||
| 関連タイプ | isIdenticalTo | |||||||||||
| 識別子タイプ | DOI | |||||||||||
| 関連識別子 | https://doi.org/10.4236/jamp.2018.68150 | |||||||||||
| ISSN | ||||||||||||
| 収録物識別子タイプ | PISSN | |||||||||||
| 収録物識別子 | 2327-4379 | |||||||||||
| ISSN | ||||||||||||
| 収録物識別子タイプ | EISSN | |||||||||||
| 収録物識別子 | 2327-4352 | |||||||||||
| 著作権関連情報 | ||||||||||||
| 権利情報Resource | http://creativecommons.org/licenses/by/4.0/ | |||||||||||
| 権利情報 | Copyright (c) 2018 by authors and Scientific Research Publishing Inc. Creative Commons Attribution 4.0 International License. | |||||||||||
| キーワード | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | Numerical Simulation | |||||||||||
| キーワード | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | Particle Model | |||||||||||
| キーワード | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | Stratum Corneum | |||||||||||
| キーワード | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | TEWL | |||||||||||
| キーワード | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | Diffusion Equation | |||||||||||
| キーワード | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | Moisture Retention | |||||||||||
| キーワード | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 出版タイプ | ||||||||||||
| 出版タイプ | VoR | |||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||
| 査読の有無 | ||||||||||||
| 値 | yes | |||||||||||
| 研究者情報 | ||||||||||||
| URL | https://hyokadb02.jimu.kyutech.ac.jp/html/256_ja.html | |||||||||||
| 論文ID（連携） | ||||||||||||
| 値 | 10334748 | |||||||||||
| 連携ID | ||||||||||||
| 値 | 7561 | |||||||||||
