@article{oai:kyutech.repo.nii.ac.jp:00006085,
 author = {Sato, Shinobu and 佐藤, しのぶ and Imaichi, Yuuki and Yoshiura, Yukiko and Nakazawa, Koji and Takenaka, Shigeori and 竹中, 繁織},
 issue = {1},
 journal = {Analytical Sciences},
 month = {Jan},
 note = {A peptide-oligonucleotide conjugate (1) was synthesized by the attachment of FAM, TAMRA, and biotin moieties to a telomere DNA sequence of 5′-TAG GGT TAG GGT TAG GGT TAG GG-3′. This conjugate was induced to be an anti-parallel structure in the presence of sodium ion (Na+), whereas a hybrid one was formed under potassium ion (K+) as a monitoring by circular dichromic spectra. The conformation change of this conjugate gave an effective FRET signal change upon the addition of NaCl, compared with the case of KCl. Under 5 mM KCl as an extracellular condition, a FRET change was observed upon addition of NaCl and quantitative FRET change was observed in 0 – 250 mM NaCl. This conjugate was immobilized on the cell surface through a sugar chain on the cell, biotinyl concanavallin A and streptavidin. This conjugate was utilized for Na+ sensing based on anti-parallel tetraplex formation with Na+.},
 pages = {85--90},
 title = {Synthesis of a Peptide-Human Telomere DNA Conjugate as a Fluorometric Imaging Reagent for Biological Sodium Ion},
 volume = {35},
 year = {2019},
 yomi = {サトウ, シノブ and タケナカ, シゲオリ}
}