{"created":"2023-05-15T11:59:37.307731+00:00","id":6129,"links":{},"metadata":{"_buckets":{"deposit":"c06bae2f-a07b-4af9-9bde-59ead7f06cb3"},"_deposit":{"created_by":3,"id":"6129","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"6129"},"status":"published"},"_oai":{"id":"oai:kyutech.repo.nii.ac.jp:00006129","sets":["8:9"]},"author_link":["25190","6749","25191","5963","25192","25193","25188","25195","25196","25194"],"item_21_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2017-03-29","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"6","bibliographicPageEnd":"1601","bibliographicPageStart":"1596","bibliographicVolumeNumber":"29","bibliographic_titles":[{"bibliographic_title":"Electroanalysis"}]}]},"item_21_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Ferrocenylnaphthalene diimide‐based electrochemical hybridization assay via a multi‐electrode chip was applied to detect the methylation frequency in the promoter region of human telomerase reverse transcriptase (hTERT) gene for clinical samples from tissues, local exfoliated oral cells from a lesion, or from entire oral cavity after their methylation specific PCRs. These methylation frequencies were increased with cancer progress as the following order: healthy volunteers, oral leukoplakia as precancerous lesion, and oral squamous cell carcinoma (OSCC). Operating characteristic analysis of the obtained current data doesn't only give excellent discrimination ability of OSCC, but also of oral leukoplakia from healthy volunteers for all samples. Sensitivity and specificity was 95% and 90%, respectively, which is a comparable with methods in practical use.","subitem_description_type":"Abstract"}]},"item_21_description_60":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Journal Article","subitem_description_type":"Other"}]},"item_21_link_62":{"attribute_name":"研究者情報","attribute_value_mlt":[{"subitem_link_url":"https://hyokadb02.jimu.kyutech.ac.jp/html/97_ja.html"}]},"item_21_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Wiley‐VCH Verlag GmbH & Co. KGaA"}]},"item_21_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1002/elan.201700028","subitem_relation_type_select":"DOI"}}]},"item_21_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright (c) 2017 Wiley-VCH Verlag GmbH&Co. KGaA, Weinheim"}]},"item_21_select_59":{"attribute_name":"査読の有無","attribute_value_mlt":[{"subitem_select_item":"yes"}]},"item_21_source_id_8":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1521-4109","subitem_source_identifier_type":"ISSN"}]},"item_21_subject_16":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"497","subitem_subject_scheme":"NDC"}]},"item_21_text_36":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Department of Science of Physical Functions, Division of Oral and Maxillofacial Surgery, Kyushu Dental University, 2-6-1 Manazuru, Kokurakitaku, Kitakyushu, Fukuoka 803-8580, Japan"},{"subitem_text_value":"Department of Applied Chemistry and Research Center for Bio-microsensing Technology, Kyushu Institute of Technology,1-1 Sensui, Tobataku, Kitakyushu, Fukuoka 804-8550, Japan"},{"subitem_text_value":"Department of Science of Physical Functions, Division of Oral and Maxillofacial Surgery, Kyushu Dental University, 2-6-1 Manazuru, Kokurakitaku, Kitakyushu, Fukuoka 803-8580, Japan"},{"subitem_text_value":"Department of Health Promotion, Division of Oral Pathology, Kyushu Dental University, 2-6-1 Manazuru, Kokurakitaku, Kitakyushu, Fukuoka 803-8580, Japan"},{"subitem_text_value":"Department of Science of Physical Functions, Division of Oral and Maxillofacial Surgery, Kyushu Dental University, 2-6-1 Manazuru, Kokurakitaku, Kitakyushu, Fukuoka 803-8580, Japan"},{"subitem_text_value":"Department of Science of Physical Functions, Division of Oral and Maxillofacial Surgery, Kyushu Dental University, 2-6-1 Manazuru, Kokurakitaku, Kitakyushu, Fukuoka 803-8580, Japan"},{"subitem_text_value":"Department of Science of Physical Functions, Division of Oral Medicine, Kyushu Dental University, 2-6-1 Manazuru, Kokurakitaku, Kitakyushu, Fukuoka 803-8580, Japan"},{"subitem_text_value":"Department of Health Promotion, Division of Oral Pathology, Kyushu Dental University, 2-6-1 Manazuru, Kokurakitaku, Kitakyushu, Fukuoka 803-8580, Japan"},{"subitem_text_value":"Department of Science of Physical Functions, Division of Oral and Maxillofacial Surgery, Kyushu Dental University, 2-6-1 Manazuru, Kokurakitaku, Kitakyushu, Fukuoka 803-8580, Japan"},{"subitem_text_value":"Department of Applied Chemistry and Research Center for Bio-microsensing Technology, Kyushu Institute of Technology,1-1 Sensui, Tobataku, Kitakyushu, Fukuoka 804-8550, Japan"}]},"item_21_text_63":{"attribute_name":"連携ID","attribute_value_mlt":[{"subitem_text_value":"7832"}]},"item_21_version_type_58":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Haraguchi,  Kazuya"}],"nameIdentifiers":[{}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[],"affiliationNames":[{"affiliationName":""}]}],"creatorNames":[{"creatorName":"Sato, Shinobu","creatorNameLang":"en"},{"creatorName":"佐藤, しのぶ","creatorNameLang":"ja"},{"creatorName":"サトウ, シノブ","creatorNameLang":"ja-Kana"}],"familyNames":[{},{},{}],"givenNames":[{},{},{}],"nameIdentifiers":[{},{},{},{}]},{"creatorNames":[{"creatorName":"Habu,  Manabu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yada,  Naomi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Hayakawa,  Mana"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Takahashi,  Osamu"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Yoshioka,  Izumi"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Matsuo,  Kou"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Tominaga,  Kazuhiro"}],"nameIdentifiers":[{}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[],"affiliationNames":[{"affiliationName":""}]}],"creatorNames":[{"creatorName":"Takenaka, Shigeori","creatorNameLang":"en"},{"creatorName":"竹中, 繁織","creatorNameLang":"ja"},{"creatorName":"タケナカ, シゲオリ","creatorNameLang":"ja-Kana"}],"familyNames":[{},{},{}],"givenNames":[{},{},{}],"nameIdentifiers":[{},{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2019-08-23"}],"displaytype":"detail","filename":"elan.201700028.pdf","filesize":[{"value":"587.9 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Coupled with Ferrocenylnaphthalene Diimide","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Oral Cancer Screening Based on Methylation Frequency Detection in hTERT Gene Using Electrochemical Hybridization Assay via a Multi‐electrode Chip Coupled with Ferrocenylnaphthalene Diimide"}]},"item_type_id":"21","owner":"3","path":["9"],"pubdate":{"attribute_name":"公開日","attribute_value":"2019-08-23"},"publish_date":"2019-08-23","publish_status":"0","recid":"6129","relation_version_is_last":true,"title":["Oral Cancer Screening Based on Methylation Frequency Detection in hTERT Gene Using Electrochemical Hybridization Assay via a Multi‐electrode Chip Coupled with Ferrocenylnaphthalene Diimide"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2024-04-02T08:38:19.414609+00:00"}