WEKO3
アイテム
Effect of Paired Associative Stimulation on Corticomotor Excitability in Chronic Smokers
http://hdl.handle.net/10228/00007646
http://hdl.handle.net/10228/000076465973c092-a4f9-4521-9a42-0fe1c900a8fa
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
brainsci9030062.pdf (539.0 kB)
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| アイテムタイプ | 学術雑誌論文 = Journal Article(1) | |||||||||||
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| 公開日 | 2020-03-04 | |||||||||||
| 資源タイプ | ||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
| 資源タイプ | journal article | |||||||||||
| タイトル | ||||||||||||
| タイトル | Effect of Paired Associative Stimulation on Corticomotor Excitability in Chronic Smokers | |||||||||||
| 言語 | en | |||||||||||
| 言語 | ||||||||||||
| 言語 | eng | |||||||||||
| 著者 |
Lavender, Andrew P.
× Lavender, Andrew P.× 小幡, 博基
WEKO
21360
× Kawashima, Noritaka× Nakazawa, Kimitaka |
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| 抄録 | ||||||||||||
| 内容記述タイプ | Abstract | |||||||||||
| 内容記述 | Chronic smoking has been shown to have deleterious effects on brain function and is an important risk factor for ischemic stroke. Reduced cortical excitability has been shown among chronic smokers compared with non-smokers to have a long-term effect and so far no study has assessed the effect of smoking on short-term motor learning. Paired associative stimulation (PAS) is a commonly used method for inducing changes in excitability of the motor cortex (M1) in a way that simulates short-term motor learning. This study employed PAS to investigate the effect of chronic cigarette smoking on plasticity of M1. Stimulator output required to elicit a motor-evoked potential (MEP) of approximately 1 mV was similar between the groups prior to PAS. MEP response to single pulse stimuli increased in the control group and remained above baseline level for at least 30 min after the intervention, but not in the smokers who showed no significant increase in MEP size. The silent period was similar between groups at all time points of the experiment. This study suggests that chronic smoking may have a negative effect on the response to PAS and infers that chronic smoking may have a deleterious effect on the adaptability of M1. | |||||||||||
| 言語 | en | |||||||||||
| 書誌情報 |
en : Brain Sciences 巻 9, 号 3, p. 62, 発行日 2019-03-15 |
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| 出版社 | ||||||||||||
| 出版者 | MDPI | |||||||||||
| DOI | ||||||||||||
| 関連タイプ | isIdenticalTo | |||||||||||
| 識別子タイプ | DOI | |||||||||||
| 関連識別子 | https://doi.org/10.3390/brainsci9030062 | |||||||||||
| ISSN | ||||||||||||
| 収録物識別子タイプ | EISSN | |||||||||||
| 収録物識別子 | 2076-3425 | |||||||||||
| 著作権関連情報 | ||||||||||||
| 権利情報Resource | https://creativecommons.org/licenses/by/4.0/ | |||||||||||
| 権利情報 | Copyright (c) 2019 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (http://creativecommons.org/licenses/by/4.0/). | |||||||||||
| キーワード | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | transcranial magnetic stimulation | |||||||||||
| キーワード | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | paired associative stimulation | |||||||||||
| キーワード | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | smoking | |||||||||||
| キーワード | ||||||||||||
| 主題Scheme | Other | |||||||||||
| 主題 | cotinine | |||||||||||
| 出版タイプ | ||||||||||||
| 出版タイプ | VoR | |||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||
| 査読の有無 | ||||||||||||
| 値 | yes | |||||||||||
| 研究者情報 | ||||||||||||
| URL | https://hyokadb02.jimu.kyutech.ac.jp/html/100000904_ja.html | |||||||||||
| 論文ID（連携） | ||||||||||||
| 値 | 10335564 | |||||||||||
| 連携ID | ||||||||||||
| 値 | 8143 | |||||||||||
