{"created":"2023-05-15T12:00:06.056134+00:00","id":6785,"links":{},"metadata":{"_buckets":{"deposit":"609c5a32-775e-406e-8195-1845b12e4ef8"},"_deposit":{"created_by":3,"id":"6785","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"6785"},"status":"published"},"_oai":{"id":"oai:kyutech.repo.nii.ac.jp:00006785","sets":["8:9"]},"author_link":["28759","6369","28757"],"item_21_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019-12-19","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"1","bibliographicPageEnd":"379","bibliographicPageStart":"372","bibliographicVolumeNumber":"17","bibliographic_titles":[{"bibliographic_title":"International Journal of Applied Ceramic Technology"}]}]},"item_21_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Octacalcium phosphate (OCP) is a key precursor of biological apatite in hard tissues with excellent osteoconductive and biodegradable properties for bone regeneration. OCP spherical granules are expected to be useful as drug delivery carriers, since OCP has high specific surface area. Although there have been some reports of OCP sphere preparation, methods for preparing pure OCP spheres are limited. The objective of this study is the preparation of spherical granules of pure OCP and assessment of their in vitro biodegradation in physiological conditions. We successfully prepared spherical pure OCP granules with a size of ~500 µm without any organic additives by simple immersion of α‐tricalcium phosphate spherical granules in pH 5.0 acetate buffered solutions at 60°C. The granules had core‐shell structure composed of OCP crystals different particle size. The spherical granules showed 20%‐40% in vitro degradation in physiological conditions; however, the phase transition of OCP was not significantly observed.","subitem_description_type":"Abstract"}]},"item_21_description_60":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Journal Article","subitem_description_type":"Other"}]},"item_21_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"28759","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Tripathi,  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Toshiki","nameLang":"en"},{"name":"宮崎, 敏樹","nameLang":"ja"},{"name":"ミヤザキ, トシキ","nameLang":"ja-Kana"}]}]},"item_21_link_62":{"attribute_name":"研究者情報","attribute_value_mlt":[{"subitem_link_url":"https://hyokadb02.jimu.kyutech.ac.jp/html/323_ja.html"}]},"item_21_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Blackwell Publishing Ltd."}]},"item_21_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1111/ijac.13371","subitem_relation_type_select":"DOI"}}]},"item_21_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright (c) 2019 The American Ceramic Society"}]},"item_21_select_59":{"attribute_name":"査読の有無","attribute_value_mlt":[{"subitem_select_item":"yes"}]},"item_21_source_id_10":{"attribute_name":"書誌レコードID","attribute_value_mlt":[{"subitem_source_identifier":"AA11926159","subitem_source_identifier_type":"NCID"}]},"item_21_source_id_8":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1546-542X","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"1744-7402","subitem_source_identifier_type":"ISSN"}]},"item_21_subject_16":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"497","subitem_subject_scheme":"NDC"}]},"item_21_text_28":{"attribute_name":"論文ID（連携）","attribute_value_mlt":[{"subitem_text_value":"10348421"}]},"item_21_text_36":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology, 2‐4, Hibikino, Wakamatsu‐ku, Kitakyushu 808‐0196, Japan"},{"subitem_text_value":"Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology, 2‐4, Hibikino, Wakamatsu‐ku, Kitakyushu 808‐0196, Japan"}]},"item_21_text_63":{"attribute_name":"連携ID","attribute_value_mlt":[{"subitem_text_value":"8011"}]},"item_21_version_type_58":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Tripathi,  Garima"}],"nameIdentifiers":[{}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[],"affiliationNames":[{"affiliationName":""}]}],"creatorNames":[{"creatorName":"Miyazaki, Toshiki","creatorNameLang":"en"},{"creatorName":"宮崎, 敏樹","creatorNameLang":"ja"},{"creatorName":"ミヤザキ, トシキ","creatorNameLang":"ja-Kana"}],"familyNames":[{},{},{}],"givenNames":[{},{},{}],"nameIdentifiers":[{},{},{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2020-12-21"}],"displaytype":"detail","filename":"ijac.13371.pdf","filesize":[{"value":"2.3 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"ijac.13371.pdf","url":"https://kyutech.repo.nii.ac.jp/record/6785/files/ijac.13371.pdf"},"version_id":"3c57ebb4-a59d-4a0a-95cd-df99921dbf86"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Acetate buffer treatment","subitem_subject_scheme":"Other"},{"subitem_subject":"in vitro biodegradation","subitem_subject_scheme":"Other"},{"subitem_subject":"Pure OCP sphere","subitem_subject_scheme":"Other"},{"subitem_subject":"α‐TCP","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Synthesis and in vitro biodegradation of pure octacalcium phosphate spheres","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Synthesis and in vitro biodegradation of pure octacalcium phosphate spheres"}]},"item_type_id":"21","owner":"3","path":["9"],"pubdate":{"attribute_name":"公開日","attribute_value":"2020-12-21"},"publish_date":"2020-12-21","publish_status":"0","recid":"6785","relation_version_is_last":true,"title":["Synthesis and in vitro biodegradation of pure octacalcium phosphate spheres"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2024-04-02T08:39:22.594359+00:00"}