WEKO3
アイテム
XOR Gate Design Toward a Practical Complete Set for DNA Computing
http://hdl.handle.net/10228/00008088
http://hdl.handle.net/10228/00008088414a79b5-67ab-4450-b26d-b5a2aca4acf8
| 名前 / ファイル | ライセンス | アクション |
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| アイテムタイプ | 学術雑誌論文 = Journal Article(1) | |||||||||||||
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| 公開日 | 2021-03-22 | |||||||||||||
| 資源タイプ | ||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||
| 資源タイプ | journal article | |||||||||||||
| タイトル | ||||||||||||||
| タイトル | XOR Gate Design Toward a Practical Complete Set for DNA Computing | |||||||||||||
| 言語 | ||||||||||||||
| 言語 | eng | |||||||||||||
| 著者 |
Nishijima, Katsuhiro
× Nishijima, Katsuhiro× 中茎, 隆
WEKO
29506
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| 抄録 | ||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||
| 内容記述 | Practical design of the XOR gate is an important milestone in the field of DNA computing. In this study, we aim to develop an enzyme-free XOR gate driven by a toehold-mediated strand displacement mechanism possessing the true detection property. The advantages of our design are as follows: dual-rail logic is not required, the explicit use of the NOT gate is avoided, the circuit structure is simple, and the design is achievable with fewer DNA strands than that designed by the combination of four NAND gates. A rational circuit design is performed and the dynamic behaviors of the biochemical reaction and the secondary structures of DNA strands are confirmed by computer simulation. In particular, both the domain-level design technique with G-T mismatched base pairs and base sequence-level fine-tuning are successfully achieved to alleviate the performance degradation arising from unintended and leaky reactions present in the circuit. The validity of the XOR gate design is confirmed by experimental studies. | |||||||||||||
| 書誌情報 |
New Generation Computing 巻 38, p. 285-301, 発行日 2020-03-21 |
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| 出版社 | ||||||||||||||
| 出版者 | Springer | |||||||||||||
| DOI | ||||||||||||||
| 関連タイプ | isVersionOf | |||||||||||||
| 識別子タイプ | DOI | |||||||||||||
| 関連識別子 | https://doi.org/10.1007/s00354-020-00090-3 | |||||||||||||
| 日本十進分類法 | ||||||||||||||
| 主題Scheme | NDC | |||||||||||||
| 主題 | 461 | |||||||||||||
| NCID | ||||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||||
| 収録物識別子 | AA10468773 | |||||||||||||
| ISSN | ||||||||||||||
| 収録物識別子タイプ | ISSN | |||||||||||||
| 収録物識別子 | 0288-3635 | |||||||||||||
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| 収録物識別子タイプ | ISSN | |||||||||||||
| 収録物識別子 | 1882-7055 | |||||||||||||
| 著作権関連情報 | ||||||||||||||
| 権利情報 | Copyright (c) Ohmsha, Ltd. and Springer Japan KK, part of Springer Nature 2020. This is a post-peer-review, pre-copyedit version of an article published in New Generation Computing. The final authenticated version is available online at: http://dx.doi.org/10.1007/s00354-020-00090-3. | |||||||||||||
| キーワード | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | Dynamic DNA nanotechnology | |||||||||||||
| キーワード | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | Strand displacement mechanism | |||||||||||||
| キーワード | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | Exclusive OR gate | |||||||||||||
| 出版タイプ | ||||||||||||||
| 出版タイプ | AM | |||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||||||||
| 査読の有無 | ||||||||||||||
| 値 | yes | |||||||||||||
| 連携ID | ||||||||||||||
| 値 | 8195 | |||||||||||||