{"created":"2023-05-15T12:00:16.331124+00:00","id":7013,"links":{},"metadata":{"_buckets":{"deposit":"68267cf1-7417-41dd-9863-64ed7b2e88aa"},"_deposit":{"created_by":3,"id":"7013","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"7013"},"status":"published"},"_oai":{"id":"oai:kyutech.repo.nii.ac.jp:00007013","sets":["8:9"]},"author_link":["6749","30260","30263","5963"],"item_21_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2019-01-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"10","bibliographicPageEnd":"1993","bibliographicPageStart":"1988","bibliographicVolumeNumber":"31","bibliographic_titles":[{"bibliographic_title":"Electroanalysis"}]}]},"item_21_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Electrochemical detection of the specific gene carrying aberrant methylated cytosine was achieved by ferrocenyl naphthalene diimide carrying β‐cyclodextrin (β‐CD), FNC, coupled with the probe‐DNA‐immobilized electrode. The five CpG sites in a 24‐base sequence were selected as the target DNA on the CDH4 gene, which is associated with colorectal cancer. When methylated and unmethylated samples hybridized with the DNA probe (HS‐M24) immobilized on the electrode, an increased current signal was observed in the electrolyte containing FNC and correlated with the amount of target DNA. Furthermore, an increase in current (115 %) was observed when the PCR product of 105 bp was hybridized on the HS‐M24‐immobilized electrode, whereas a background level of current increase was observed in the case of unmethylated product. Such large discrimination ability might be due to the inter‐ and/or intra‐complex formation of ferrocene with β‐CD of FNC on the surface of the electrode.","subitem_description_type":"Abstract"}]},"item_21_description_60":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Journal Article","subitem_description_type":"Other"}]},"item_21_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"affiliations":[{"affiliationNames":[{"affiliationName":"","lang":"ja"}],"nameIdentifiers":[]}],"familyNames":[{"familyName":"Sato","familyNameLang":"en"},{"familyName":"佐藤","familyNameLang":"ja"},{"familyName":"サトウ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Shinobu","givenNameLang":"en"},{"givenName":"しのぶ","givenNameLang":"ja"},{"givenName":"シノブ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"5963","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"80510677","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/nrid/1000080510677"},{"nameIdentifier":"7501769466","nameIdentifierScheme":"Scopus著者ID","nameIdentifierURI":"https://www.scopus.com/authid/detail.uri?authorId=7501769466"},{"nameIdentifier":"395","nameIdentifierScheme":"九工大研究者情報","nameIdentifierURI":"https://hyokadb02.jimu.kyutech.ac.jp/html/395_ja.html"}],"names":[{"name":"Sato, Shinobu","nameLang":"en"},{"name":"佐藤, しのぶ","nameLang":"ja"},{"name":"サトウ, シノブ","nameLang":"ja-Kana"}]},{"nameIdentifiers":[{"nameIdentifier":"30263","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Nishi,  Y."}]},{"affiliations":[{"affiliationNames":[{"affiliationName":"","lang":"ja"}],"nameIdentifiers":[]}],"familyNames":[{"familyName":"Takenaka","familyNameLang":"en"},{"familyName":"竹中","familyNameLang":"ja"},{"familyName":"タケナカ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Shigeori","givenNameLang":"en"},{"givenName":"繁織","givenNameLang":"ja"},{"givenName":"シゲオリ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"6749","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"60188208","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/nrid/1000060188208"},{"nameIdentifier":"7202789037","nameIdentifierScheme":"Scopus著者ID","nameIdentifierURI":"https://www.scopus.com/authid/detail.uri?authorId=7202789037"},{"nameIdentifier":"97","nameIdentifierScheme":"九工大研究者情報","nameIdentifierURI":"https://hyokadb02.jimu.kyutech.ac.jp/html/97_ja.html"}],"names":[{"name":"Takenaka, Shigeori","nameLang":"en"},{"name":"竹中, 繁織","nameLang":"ja"},{"name":"タケナカ, シゲオリ","nameLang":"ja-Kana"}]}]},"item_21_link_62":{"attribute_name":"研究者情報","attribute_value_mlt":[{"subitem_link_url":"https://hyokadb02.jimu.kyutech.ac.jp/html/97_ja.html"}]},"item_21_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Wiley‐VCH Verlag GmbH & Co. KGaA"}]},"item_21_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1002/elan.201900282","subitem_relation_type_select":"DOI"}}]},"item_21_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright (c) 2019 Wiley‐VCH Verlag GmbH & Co. KGaA, Weinheim"}]},"item_21_select_59":{"attribute_name":"査読の有無","attribute_value_mlt":[{"subitem_select_item":"yes"}]},"item_21_source_id_8":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1521-4109","subitem_source_identifier_type":"ISSN"}]},"item_21_subject_16":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"464","subitem_subject_scheme":"NDC"}]},"item_21_text_28":{"attribute_name":"論文ID（連携）","attribute_value_mlt":[{"subitem_text_value":"10344701"}]},"item_21_text_36":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Department of Applied Chemistry, Kyushu Institute of Technology, Fukuoka 804-8550, Japan, Research Center for Bio-microsensing Technology, Kyushu Institute of Technology, Fukuoka 804-8550, Japan"},{"subitem_text_value":"Department of Applied Chemistry, Kyushu Institute of Technology, Fukuoka 804-8550, Japan"},{"subitem_text_value":"Department of Applied Chemistry, Kyushu Institute of Technology, Fukuoka 804-8550, Japan, Research Center for Bio-microsensing Technology, Kyushu Institute of Technology, Fukuoka 804-8550, Japan"}]},"item_21_text_63":{"attribute_name":"連携ID","attribute_value_mlt":[{"subitem_text_value":"8735"}]},"item_21_version_type_58":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[],"affiliationNames":[{"affiliationName":""}]}],"creatorNames":[{"creatorName":"Sato, Shinobu","creatorNameLang":"en"},{"creatorName":"佐藤, しのぶ","creatorNameLang":"ja"},{"creatorName":"サトウ, シノブ","creatorNameLang":"ja-Kana"}],"familyNames":[{},{},{}],"givenNames":[{},{},{}],"nameIdentifiers":[{},{},{},{}]},{"creatorNames":[{"creatorName":"Nishi,  Yukiko"}],"nameIdentifiers":[{}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[],"affiliationNames":[{"affiliationName":""}]}],"creatorNames":[{"creatorName":"Takenaka, Shigeori","creatorNameLang":"en"},{"creatorName":"竹中, 繁織","creatorNameLang":"ja"},{"creatorName":"タケナカ, シゲオリ","creatorNameLang":"ja-Kana"}],"familyNames":[{},{},{}],"givenNames":[{},{},{}],"nameIdentifiers":[{},{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-04-22"}],"displaytype":"detail","filename":"10344701.pdf","filesize":[{"value":"363.4 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"10344701.pdf","url":"https://kyutech.repo.nii.ac.jp/record/7013/files/10344701.pdf"},"version_id":"91eac121-6eaa-46fa-b026-e4034b864730"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"aberrant methylation","subitem_subject_scheme":"Other"},{"subitem_subject":"cyclodextrin","subitem_subject_scheme":"Other"},{"subitem_subject":"electrochemical hybridization assay","subitem_subject_scheme":"Other"},{"subitem_subject":"ferrocene","subitem_subject_scheme":"Other"},{"subitem_subject":"naphthalene diimide derivative","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Electrochemical Aberrant Methylation Detection Based on Ferrocenyl Naphthalene Diimide Carrying β-cyclodextrin, FNC","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Electrochemical Aberrant Methylation Detection Based on Ferrocenyl Naphthalene Diimide Carrying β-cyclodextrin, FNC"}]},"item_type_id":"21","owner":"3","path":["9"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-04-22"},"publish_date":"2021-04-22","publish_status":"0","recid":"7013","relation_version_is_last":true,"title":["Electrochemical Aberrant Methylation Detection Based on Ferrocenyl Naphthalene Diimide Carrying β-cyclodextrin, FNC"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2024-04-02T08:41:15.991202+00:00"}