{"created":"2023-05-15T12:00:21.952303+00:00","id":7141,"links":{},"metadata":{"_buckets":{"deposit":"86788745-dd6b-4fe0-9771-7e605eedc3d8"},"_deposit":{"created_by":3,"id":"7141","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"7141"},"status":"published"},"_oai":{"id":"oai:kyutech.repo.nii.ac.jp:00007141","sets":["8:24"]},"author_link":["6369","30744","30742","30745","30741"],"item_21_alternative_title_18":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Release profiles of dyes and proteins from calcium phosphate microspheres with different crystalline phase"}]},"item_21_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-06-06","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"301","bibliographicPageStart":"291","bibliographicVolumeNumber":"4","bibliographic_titles":[{"bibliographic_title":"Ceramics"}]}]},"item_21_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Calcium phosphate is attracting attention as a bone repair material and a controlled-release carrier of various drugs such as bone disease therapeutic agents and anticancer agents. Compared with some bioabsorbable polymers, calcium phosphates have the advantage of preventing a pH decrease in the surrounding body fluid. However, there are few studies comparing the effect of supporting substances with different physicochemical properties on the production of calcium phosphate microspheres with different crystalline phases. In this study, we investigated conditions for obtaining low crystallinity apatite and octacalcium phosphate (OCP) microspheres from calcium carbonate microspheres with different crystalline structures using a simple phosphoric acid treatment. Furthermore, we investigated the adsorption and release behavior of different dyes and proteins from the apatite and OCP microspheres. Overall, the factors governing the adsorption and release behavior are different depending on the molecular size and surface charge of the dye and protein adsorbates.","subitem_description_type":"Abstract"}]},"item_21_description_60":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Journal Article","subitem_description_type":"Other"}]},"item_21_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"affiliations":[{"affiliationNames":[{"affiliationName":"","lang":"ja"}],"nameIdentifiers":[]}],"familyNames":[{"familyName":"Miyazaki","familyNameLang":"en"},{"familyName":"宮崎","familyNameLang":"ja"},{"familyName":"ミヤザキ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Toshiki","givenNameLang":"en"},{"givenName":"敏樹","givenNameLang":"ja"},{"givenName":"トシキ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"6369","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"20324973","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/nrid/1000020324973"},{"nameIdentifier":"7404107414","nameIdentifierScheme":"Scopus著者ID","nameIdentifierURI":"https://www.scopus.com/authid/detail.uri?authorId=7404107414"},{"nameIdentifier":"0000-0001-5642-0096","nameIdentifierScheme":"ORCiD","nameIdentifierURI":"https://orcid.org/0000-0001-5642-0096"},{"nameIdentifier":"323","nameIdentifierScheme":"九工大研究者情報","nameIdentifierURI":"https://hyokadb02.jimu.kyutech.ac.jp/html/323_ja.html"}],"names":[{"name":"Miyazaki, Toshiki","nameLang":"en"},{"name":"宮崎, 敏樹","nameLang":"ja"},{"name":"ミヤザキ, トシキ","nameLang":"ja-Kana"}]},{"nameIdentifiers":[{"nameIdentifier":"30744","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Masuda,  K."}]},{"nameIdentifiers":[{"nameIdentifier":"30745","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Sakamoto,  K."}]}]},"item_21_link_62":{"attribute_name":"研究者情報","attribute_value_mlt":[{"subitem_link_url":"https://hyokadb02.jimu.kyutech.ac.jp/html/323_ja.html"}]},"item_21_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"MDPI"}]},"item_21_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.3390/ceramics4020023","subitem_relation_type_select":"DOI"}}]},"item_21_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Copyright (c) 2021 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/)."}]},"item_21_select_59":{"attribute_name":"査読の有無","attribute_value_mlt":[{"subitem_select_item":"yes"}]},"item_21_source_id_8":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"2571-6131","subitem_source_identifier_type":"ISSN"}]},"item_21_subject_16":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"573","subitem_subject_scheme":"NDC"}]},"item_21_text_28":{"attribute_name":"論文ID（連携）","attribute_value_mlt":[{"subitem_text_value":"10364608"}]},"item_21_text_36":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Kyushu Institute of Technology"},{"subitem_text_value":"Kyushu Institute of Technology"},{"subitem_text_value":"Kyushu Institute of Technology"}]},"item_21_text_63":{"attribute_name":"連携ID","attribute_value_mlt":[{"subitem_text_value":"8941"}]},"item_21_version_type_58":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorAffiliations":[{"affiliationNameIdentifiers":[],"affiliationNames":[{"affiliationName":""}]}],"creatorNames":[{"creatorName":"Miyazaki, Toshiki","creatorNameLang":"en"},{"creatorName":"宮崎, 敏樹","creatorNameLang":"ja"},{"creatorName":"ミヤザキ, トシキ","creatorNameLang":"ja-Kana"}],"familyNames":[{},{},{}],"givenNames":[{},{},{}],"nameIdentifiers":[{},{},{},{},{}]},{"creatorNames":[{"creatorName":"Masuda,  Koudai"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Sakamoto,  Kazuki"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-06-08"}],"displaytype":"detail","filename":"ceramics-04-00023.pdf","filesize":[{"value":"950.5 kB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"ceramics-04-00023.pdf","url":"https://kyutech.repo.nii.ac.jp/record/7141/files/ceramics-04-00023.pdf"},"version_id":"a892cf31-b646-4241-a206-801d8c4f4cb7"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"apatite","subitem_subject_scheme":"Other"},{"subitem_subject":"octacalcium phosphate (OCP)","subitem_subject_scheme":"Other"},{"subitem_subject":"microsphere","subitem_subject_scheme":"Other"},{"subitem_subject":"drug delivery","subitem_subject_scheme":"Other"},{"subitem_subject":"dye","subitem_subject_scheme":"Other"},{"subitem_subject":"protein","subitem_subject_scheme":"Other"},{"subitem_subject":"mesopore","subitem_subject_scheme":"Other"},{"subitem_subject":"surface charge","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Release Profiles of Dyes and Proteins from Calcium Phosphate Microspheres with Different Crystalline Phases","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Release Profiles of Dyes and Proteins from Calcium Phosphate Microspheres with Different Crystalline Phases"}]},"item_type_id":"21","owner":"3","path":["24"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-06-08"},"publish_date":"2021-06-08","publish_status":"0","recid":"7141","relation_version_is_last":true,"title":["Release Profiles of Dyes and Proteins from Calcium Phosphate Microspheres with Different Crystalline Phases"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2023-10-25T09:45:46.443184+00:00"}