{"created":"2023-05-15T12:00:24.714411+00:00","id":7205,"links":{},"metadata":{"_buckets":{"deposit":"162e6467-39c9-44f3-9e11-73d62ba3557b"},"_deposit":{"created_by":3,"id":"7205","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"7205"},"status":"published"},"_oai":{"id":"oai:kyutech.repo.nii.ac.jp:00007205","sets":["8:9"]},"author_link":["31035","31038","6369","649"],"item_21_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-03-24","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"2","bibliographicPageEnd":"320","bibliographicPageStart":"311","bibliographicVolumeNumber":"36","bibliographic_titles":[{"bibliographic_title":"Journal of Biomaterials Applications"}]}]},"item_21_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Bone cement based on poly(methyl methacrylate) (PMMA) powder and methyl methacrylate (MMA) liquid is a very popular biomaterial used for the fixation of artificial joints. However, there is a risk of this cement loosening from bone because of a lack of bone-bonding bioactivity. Apatite formation in the body environment is a prerequisite for cement bioactivity. Additionally, suppression of infection during implantation is required for bone cements to be successfully introduced into the human body. In this study, we modified PMMA cement with γ-methacryloxypropyltrimetoxysilane and calcium acetate to introduce bioactive properties and 2-(tert-butylamino)ethyl methacrylate (TBAEMA) to provide antibacterial properties. The long-term antibacterial activity is attributed to the copolymerization of TBAEMA and MMA. As the TBAEMA content increased, the setting time increased and the compressive strength decreased. After soaking in simulated body fluid, an apatite layer was detected within 7 days, irrespective of the TBAEMA content. The cement showed better antibacterial activity against Gram-negative E. Coli than Gram-positive bacteria; however, of the Gram-positive bacteria investigated, B. subtilis was more susceptible than S. aureus.","subitem_description_type":"Abstract"}]},"item_21_description_60":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Journal Article","subitem_description_type":"Other"}]},"item_21_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"31038","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Wang,  H."}]},{"affiliations":[{"affiliationNames":[{"affiliationName":"","lang":"ja"}],"nameIdentifiers":[]}],"familyNames":[{"familyName":"Maeda","familyNameLang":"en"},{"familyName":"前田","familyNameLang":"ja"},{"familyName":"マエダ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Toshinari","givenNameLang":"en"},{"givenName":"憲成","givenNameLang":"ja"},{"givenName":"トシナリ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"649","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"00470592","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/nrid/1000000470592"},{"nameIdentifier":"57212755607","nameIdentifierScheme":"Scopus著者ID","nameIdentifierURI":"https://www.scopus.com/authid/detail.uri?authorId=57212755607"},{"nameIdentifier":"333","nameIdentifierScheme":"九工大研究者情報","nameIdentifierURI":"https://hyokadb02.jimu.kyutech.ac.jp/html/333_ja.html"}],"names":[{"name":"Maeda, Toshinari","nameLang":"en"},{"name":"前田, 憲成","nameLang":"ja"},{"name":"マエダ, トシナリ","nameLang":"ja-Kana"}]},{"affiliations":[{"affiliationNames":[{"affiliationName":"","lang":"ja"}],"nameIdentifiers":[]}],"familyNames":[{"familyName":"Miyazaki","familyNameLang":"en"},{"familyName":"宮崎","familyNameLang":"ja"},{"familyName":"ミヤザキ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Toshiki","givenNameLang":"en"},{"givenName":"敏樹","givenNameLang":"ja"},{"givenName":"トシキ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"6369","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"20324973","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/nrid/1000020324973"},{"nameIdentifier":"7404107414","nameIdentifierScheme":"Scopus著者ID","nameIdentifierURI":"https://www.scopus.com/authid/detail.uri?authorId=7404107414"},{"nameIdentifier":"0000-0001-5642-0096","nameIdentifierScheme":"ORCiD","nameIdentifierURI":"https://orcid.org/0000-0001-5642-0096"},{"nameIdentifier":"323","nameIdentifierScheme":"九工大研究者情報","nameIdentifierURI":"https://hyokadb02.jimu.kyutech.ac.jp/html/323_ja.html"}],"names":[{"name":"Miyazaki, Toshiki","nameLang":"en"},{"name":"宮崎, 敏樹","nameLang":"ja"},{"name":"ミヤザキ, トシキ","nameLang":"ja-Kana"}]}]},"item_21_link_62":{"attribute_name":"研究者情報","attribute_value_mlt":[{"subitem_link_url":"https://hyokadb02.jimu.kyutech.ac.jp/html/323_ja.html"}]},"item_21_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Sage Publications"}]},"item_21_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isVersionOf","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.1177/08853282211004413","subitem_relation_type_select":"DOI"}}]},"item_21_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"Haiyang Wang, Toshinari Maeda, Toshiki Miyazaki, Preparation of bioactive and antibacterial PMMA-based bone cement by modification with quaternary ammonium and alkoxysilane,  Journal of Biomaterials Applications (vol.36 Issue2) pp. 311-320. Copyright (c) 2021 SAGE Publications. DOI: 10.1177/08853282211004413."}]},"item_21_select_59":{"attribute_name":"査読の有無","attribute_value_mlt":[{"subitem_select_item":"yes"}]},"item_21_source_id_8":{"attribute_name":"ISSN","attribute_value_mlt":[{"subitem_source_identifier":"1530-8022","subitem_source_identifier_type":"ISSN"},{"subitem_source_identifier":"0885-3282  ","subitem_source_identifier_type":"ISSN"}]},"item_21_subject_16":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"492","subitem_subject_scheme":"NDC"}]},"item_21_text_28":{"attribute_name":"論文ID（連携）","attribute_value_mlt":[{"subitem_text_value":"10374493"}]},"item_21_text_36":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Kyushu Institute of Technology"},{"subitem_text_value":"Kyushu Institute of Technology"},{"subitem_text_value":"Kyushu Institute of Technology"}]},"item_21_text_63":{"attribute_name":"連携ID","attribute_value_mlt":[{"subitem_text_value":"9037"}]},"item_21_version_type_58":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_ab4af688f83e57aa","subitem_version_type":"AM"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Wang,  Haiyang"}],"nameIdentifiers":[{}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[],"affiliationNames":[{"affiliationName":""}]}],"creatorNames":[{"creatorName":"Maeda, Toshinari","creatorNameLang":"en"},{"creatorName":"前田, 憲成","creatorNameLang":"ja"},{"creatorName":"マエダ, トシナリ","creatorNameLang":"ja-Kana"}],"familyNames":[{},{},{}],"givenNames":[{},{},{}],"nameIdentifiers":[{},{},{},{}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[],"affiliationNames":[{"affiliationName":""}]}],"creatorNames":[{"creatorName":"Miyazaki, Toshiki","creatorNameLang":"en"},{"creatorName":"宮崎, 敏樹","creatorNameLang":"ja"},{"creatorName":"ミヤザキ, トシキ","creatorNameLang":"ja-Kana"}],"familyNames":[{},{},{}],"givenNames":[{},{},{}],"nameIdentifiers":[{},{},{},{},{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2021-07-29"}],"displaytype":"detail","filename":"08853282211004413.pdf","filesize":[{"value":"2.4 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"08853282211004413.pdf","url":"https://kyutech.repo.nii.ac.jp/record/7205/files/08853282211004413.pdf"},"version_id":"63d6efe6-47a2-4cb9-ba73-120afd4e37c5"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"PMMA bone cement","subitem_subject_scheme":"Other"},{"subitem_subject":"2-(tert-butylamino)ethyl methacrylate","subitem_subject_scheme":"Other"},{"subitem_subject":"mechanical property","subitem_subject_scheme":"Other"},{"subitem_subject":"apatite formation","subitem_subject_scheme":"Other"},{"subitem_subject":"antibacterial activity","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Preparation of bioactive and antibacterial PMMA-based bone cement by modification with quaternary ammonium and alkoxysilane","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Preparation of bioactive and antibacterial PMMA-based bone cement by modification with quaternary ammonium and alkoxysilane"}]},"item_type_id":"21","owner":"3","path":["9"],"pubdate":{"attribute_name":"公開日","attribute_value":"2021-07-29"},"publish_date":"2021-07-29","publish_status":"0","recid":"7205","relation_version_is_last":true,"title":["Preparation of bioactive and antibacterial PMMA-based bone cement by modification with quaternary ammonium and alkoxysilane"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2024-04-02T08:39:20.157614+00:00"}