{"created":"2023-05-15T12:00:39.764832+00:00","id":7563,"links":{},"metadata":{"_buckets":{"deposit":"b7417c38-750f-4e4c-a54c-7107c0cc31a8"},"_deposit":{"created_by":3,"id":"7563","owners":[3],"pid":{"revision_id":0,"type":"depid","value":"7563"},"status":"published"},"_oai":{"id":"oai:kyutech.repo.nii.ac.jp:00007563","sets":["8:9"]},"author_link":["15664","32656","6369","32660","32661","32663","32655","32662","32657","32666"],"item_21_alternative_title_18":{"attribute_name":"その他のタイトル","attribute_value_mlt":[{"subitem_alternative_title":"Preparation and Characterization of PLGA Encapsulated Tamoxifen Citrate-Magnetite Nanoparticle Via Oil in Water Emulsion Evaporation Technique"}]},"item_21_biblio_info_6":{"attribute_name":"書誌情報","attribute_value_mlt":[{"bibliographicIssueDates":{"bibliographicIssueDate":"2021-11-01","bibliographicIssueDateType":"Issued"},"bibliographicIssueNumber":"4","bibliographicPageEnd":"346","bibliographicPageStart":"337","bibliographicVolumeNumber":"6","bibliographic_titles":[{"bibliographic_title":"Nanomedicine Research Journal"}]}]},"item_21_description_4":{"attribute_name":"抄録","attribute_value_mlt":[{"subitem_description":"Current research had successfully encapsulated magnetic nanoparticles (MNP) with selective estrogen receptor drug tamoxifen citrate (TAM) using Poly (d,l-lactice-co-glycolide acid) (PLGA 75:25) via oil in water emulsion technique. TAM is a good example of a drug that is difficult to dissolve. TAM is currently approved for the treatment of hormone-sensitive and early-stage breast cancer as an adjuvant endocrine therapy. The majority of the prescription medicine in today market is made up of poorly soluble, bioavailable, and quickly metabolized and eliminated drug which is a continuously challenges up to these days. Therefore, it is imperative to overcome this disadvantages by encapsulating TAM inside PLGA together with MNP for improved drug delivery. The MNP coated with oleic acid (OA) was synthesized using co-precipitation method and it is known as OAMNP. The fabricated nanohybrid is known as TAM-PLGA-OAMNP where the TAM was encapsulated together with OAMNP within PLGA. XRD results showed that OAMNP is Fe3O4. FTIR spectra revealed that the TAM was successfully encased into the PLGA structure. TAM-PLGA-OAMNP average size is about 131 ± 28 nm as shown in TEM results. The nanohybrid nanoparticles showed the absence of hysteresis loop indicative of superparamagnetic properties.","subitem_description_type":"Abstract"}]},"item_21_description_60":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"subitem_description":"Journal Article","subitem_description_type":"Other"}]},"item_21_full_name_3":{"attribute_name":"著者別名","attribute_value_mlt":[{"nameIdentifiers":[{"nameIdentifier":"32661","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Albert,  E.L."}]},{"nameIdentifiers":[{"nameIdentifier":"32662","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Abdullah,  C.A.C."}]},{"nameIdentifiers":[{"nameIdentifier":"32663","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Bahmanrokh,  G."}]},{"affiliations":[{"affiliationNames":[{"affiliationName":"","lang":"ja"}],"nameIdentifiers":[]}],"familyNames":[{"familyName":"Shirosaki","familyNameLang":"en"},{"familyName":"城崎","familyNameLang":"ja"},{"familyName":"シロサキ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Yuki","givenNameLang":"en"},{"givenName":"由紀","givenNameLang":"ja"},{"givenName":"ユキ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"15664","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"40533956","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/nrid/1000040533956"},{"nameIdentifier":"6507486862","nameIdentifierScheme":"Scopus著者ID","nameIdentifierURI":"https://www.scopus.com/authid/detail.uri?authorId=6507486862"},{"nameIdentifier":"0000-0003-4207-4393","nameIdentifierScheme":"ORCiD","nameIdentifierURI":"https://orcid.org/0000-0003-4207-4393"},{"nameIdentifier":"100000586","nameIdentifierScheme":"九工大研究者情報","nameIdentifierURI":"https://hyokadb02.jimu.kyutech.ac.jp/html/100000586_ja.html"}],"names":[{"name":"Shirosaki, Yuki","nameLang":"en"},{"name":"城崎, 由紀","nameLang":"ja"},{"name":"シロサキ, ユキ","nameLang":"ja-Kana"}]},{"affiliations":[{"affiliationNames":[{"affiliationName":"","lang":"ja"}],"nameIdentifiers":[]}],"familyNames":[{"familyName":"Miyazaki","familyNameLang":"en"},{"familyName":"宮崎","familyNameLang":"ja"},{"familyName":"ミヤザキ","familyNameLang":"ja-Kana"}],"givenNames":[{"givenName":"Toshiki","givenNameLang":"en"},{"givenName":"敏樹","givenNameLang":"ja"},{"givenName":"トシキ","givenNameLang":"ja-Kana"}],"nameIdentifiers":[{"nameIdentifier":"6369","nameIdentifierScheme":"WEKO"},{"nameIdentifier":"20324973","nameIdentifierScheme":"e-Rad","nameIdentifierURI":"https://nrid.nii.ac.jp/ja/nrid/1000020324973"},{"nameIdentifier":"7404107414","nameIdentifierScheme":"Scopus著者ID","nameIdentifierURI":"https://www.scopus.com/authid/detail.uri?authorId=7404107414"},{"nameIdentifier":"0000-0001-5642-0096","nameIdentifierScheme":"ORCiD","nameIdentifierURI":"https://orcid.org/0000-0001-5642-0096"},{"nameIdentifier":"323","nameIdentifierScheme":"九工大研究者情報","nameIdentifierURI":"https://hyokadb02.jimu.kyutech.ac.jp/html/323_ja.html"}],"names":[{"name":"Miyazaki, Toshiki","nameLang":"en"},{"name":"宮崎, 敏樹","nameLang":"ja"},{"name":"ミヤザキ, トシキ","nameLang":"ja-Kana"}]},{"nameIdentifiers":[{"nameIdentifier":"32666","nameIdentifierScheme":"WEKO"}],"names":[{"name":"Yaacob,  S.N."}]}]},"item_21_link_62":{"attribute_name":"研究者情報","attribute_value_mlt":[{"subitem_link_url":"https://hyokadb02.jimu.kyutech.ac.jp/html/323_ja.html"}]},"item_21_publisher_7":{"attribute_name":"出版者","attribute_value_mlt":[{"subitem_publisher":"Iranian Society of Nanomedicine"}]},"item_21_relation_12":{"attribute_name":"DOI","attribute_value_mlt":[{"subitem_relation_type":"isIdenticalTo","subitem_relation_type_id":{"subitem_relation_type_id_text":"https://doi.org/10.22034/NMRJ.2021.04.003","subitem_relation_type_select":"DOI"}}]},"item_21_rights_13":{"attribute_name":"権利","attribute_value_mlt":[{"subitem_rights":"This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/."}]},"item_21_select_59":{"attribute_name":"査読の有無","attribute_value_mlt":[{"subitem_select_item":"yes"}]},"item_21_subject_16":{"attribute_name":"日本十進分類法","attribute_value_mlt":[{"subitem_subject":"431","subitem_subject_scheme":"NDC"}]},"item_21_text_28":{"attribute_name":"論文ID（連携）","attribute_value_mlt":[{"subitem_text_value":"10388679"}]},"item_21_text_36":{"attribute_name":"著者所属","attribute_value_mlt":[{"subitem_text_value":"Universiti Putra Malaysia"},{"subitem_text_value":"Universiti Putra Malaysia"},{"subitem_text_value":"Universiti Putra Malaysia"},{"subitem_text_value":"Kyushu Institute of Technology"},{"subitem_text_value":"Kyushu Institute of Technology"},{"subitem_text_value":"Universiti Putra Malaysia"}]},"item_21_text_63":{"attribute_name":"連携ID","attribute_value_mlt":[{"subitem_text_value":"10193"}]},"item_21_version_type_58":{"attribute_name":"著者版フラグ","attribute_value_mlt":[{"subitem_version_resource":"http://purl.org/coar/version/c_970fb48d4fbd8a85","subitem_version_type":"VoR"}]},"item_creator":{"attribute_name":"著者","attribute_type":"creator","attribute_value_mlt":[{"creatorNames":[{"creatorName":"Albert,  Emmellie Laura"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Abdullah,  Che Azurahanim Che"}],"nameIdentifiers":[{}]},{"creatorNames":[{"creatorName":"Bahmanrokh,  Ghazaleh"}],"nameIdentifiers":[{}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[],"affiliationNames":[{"affiliationName":""}]}],"creatorNames":[{"creatorName":"Shirosaki, Yuki","creatorNameLang":"en"},{"creatorName":"城崎, 由紀","creatorNameLang":"ja"},{"creatorName":"シロサキ, ユキ","creatorNameLang":"ja-Kana"}],"familyNames":[{},{},{}],"givenNames":[{},{},{}],"nameIdentifiers":[{},{},{},{},{}]},{"creatorAffiliations":[{"affiliationNameIdentifiers":[],"affiliationNames":[{"affiliationName":""}]}],"creatorNames":[{"creatorName":"Miyazaki, Toshiki","creatorNameLang":"en"},{"creatorName":"宮崎, 敏樹","creatorNameLang":"ja"},{"creatorName":"ミヤザキ, トシキ","creatorNameLang":"ja-Kana"}],"familyNames":[{},{},{}],"givenNames":[{},{},{}],"nameIdentifiers":[{},{},{},{},{}]},{"creatorNames":[{"creatorName":"Yaacob,  Siti Norzulfikaini"}],"nameIdentifiers":[{}]}]},"item_files":{"attribute_name":"ファイル情報","attribute_type":"file","attribute_value_mlt":[{"accessrole":"open_date","date":[{"dateType":"Available","dateValue":"2022-03-14"}],"displaytype":"detail","filename":"NMRJ_Volume6_Issue4_Pages337-346.pdf","filesize":[{"value":"1.1 MB"}],"format":"application/pdf","licensetype":"license_note","mimetype":"application/pdf","url":{"label":"NMRJ_Volume6_Issue4_Pages337-346.pdf","url":"https://kyutech.repo.nii.ac.jp/record/7563/files/NMRJ_Volume6_Issue4_Pages337-346.pdf"},"version_id":"5380039f-64ba-4b31-a022-28d3edabd3c5"}]},"item_keyword":{"attribute_name":"キーワード","attribute_value_mlt":[{"subitem_subject":"Magnetite nanoparticle","subitem_subject_scheme":"Other"},{"subitem_subject":"Tamoxifen citrate","subitem_subject_scheme":"Other"},{"subitem_subject":"Poly (d l-lactice-co-glycolide acid)","subitem_subject_scheme":"Other"}]},"item_language":{"attribute_name":"言語","attribute_value_mlt":[{"subitem_language":"eng"}]},"item_resource_type":{"attribute_name":"資源タイプ","attribute_value_mlt":[{"resourcetype":"journal article","resourceuri":"http://purl.org/coar/resource_type/c_6501"}]},"item_title":"Preparation and Characterization of Encapsulated Tamoxifen Citrate-Magnetite Nanoparticle via Oil in Water Emulsion Evaporation Technique","item_titles":{"attribute_name":"タイトル","attribute_value_mlt":[{"subitem_title":"Preparation and Characterization of Encapsulated Tamoxifen Citrate-Magnetite Nanoparticle via Oil in Water Emulsion Evaporation Technique"}]},"item_type_id":"21","owner":"3","path":["9"],"pubdate":{"attribute_name":"公開日","attribute_value":"2022-03-14"},"publish_date":"2022-03-14","publish_status":"0","recid":"7563","relation_version_is_last":true,"title":["Preparation and Characterization of Encapsulated Tamoxifen Citrate-Magnetite Nanoparticle via Oil in Water Emulsion Evaporation Technique"],"weko_creator_id":"3","weko_shared_id":3},"updated":"2024-04-02T08:45:42.184524+00:00"}