@article{oai:kyutech.repo.nii.ac.jp:00007864, author = {Uemura, Tomoki and Näppi, Janne J. and Watari, Chinatsu and Hironaka, Toru and Kamiya, Tohru and 神谷, 亨 and Yoshida, Hiroyuki}, journal = {Medical Imaging Analysis}, month = {Jul}, note = {Because of the rapid spread and wide range of the clinical manifestations of the coronavirus disease 2019 (COVID-19), fast and accurate estimation of the disease progression and mortality is vital for the management of the patients. Currently available image-based prognostic predictors for patients with COVID-19 are largely limited to semi-automated schemes with manually designed features and supervised learning, and the survival analysis is largely limited to logistic regression. We developed a weakly unsupervised conditional generative adversarial network, called pix2surv, which can be trained to estimate the time-to-event information for survival analysis directly from the chest computed tomography (CT) images of a patient. We show that the performance of pix2surv based on CT images significantly outperforms those of existing laboratory tests and image-based visual and quantitative predictors in estimating the disease progression and mortality of COVID-19 patients. Thus, pix2surv is a promising approach for performing image-based prognostic predictions.}, pages = {102159-1--102159-14}, title = {Weakly unsupervised conditional generative adversarial network for image-based prognostic prediction for COVID-19 patients based on chest CT}, volume = {73}, year = {2021}, yomi = {カミヤ, トオル} }