doi:info:doi/10.1088/1742-6596/924/1/012006

Photophysical Characterization and BSA Interaction of Direct Ring Carboxy Functionalized Symmetrical squaraine Dyes 利用統計を見る

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アイテムタイプ	学術雑誌論文 = Journal Article
言語	英語
著者	Saikiran Maryala Pandey Shyam S Hayase Shuzi Kato Tamaki
著者所属	Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology
抄録	A series of far-red sensitive symmetrical squaraine dyes bearing direct –COOH functionalized indole ring were synthesized, characterized and subjected to photophysical investigations. These symmetrical squaraine dyes were then subjected to investigate their interaction with bovine serum albumin (BSA) in Phosphate buffer solutions. All the squaraine dyes under investigation exhibit intense and sharp optical absorption mainly in the far-red wavelength region from 550 nm -700 nm having very high molar extinction coefficients from 1.3 × 105 dm3.mol−1.cm−1. A very small Stokes shift of 10-17 nm indicates the rigid conformational structure of squaraine chromophore. Interaction of these dyes with BSA leads to not only enhanced emission intensity but also bathochromically shifted absorption maximum due to formation of dye-BSA conjugate. These dyes bind strongly with BSA having about an order of magnitude higher binding constant as compared to the reported squaraine dyes. Amongst the symmetrical squaraine dyes investigated in this work one bearing substituents like trifluorobutyl as alkyl chain at N-position of indole ring and carboxylic acid on benzene ring at the terminal (SQ-26) exhibited highest association with the BSA having very high binding constant 8.01 × 106 M−1.
内容記述	12th International Conference on Nanomolecular Electronics (ICNME-2016), December 14-16, 2016, Kobe International Conference Center, Kobe, Japan
雑誌名	Journal of Physics: Conference Series
巻	924
号	1
ページ	012006-1 - 012006-10
発行年	2017-11
出版者	IOP Publishing
ISSN	1742-6588 1742-6596
DOI	info:doi/10.1088/1742-6596/924/1/012006
権利	IOP Publishing This is an author-created, un-copyedited version of an article published in Journal of Physics: Conference Series. IOP Publishing Ltd is not responsible for any errors or omissions in this version of the manuscript or any version derived from it. This article is published under a CC BY licence. The Version of Record is available online at https://doi.org/10.1088/1742-6596/924/1/012006.
情報源	https://doi.org/10.1088/1742-6596/924/1/012006
版	publisher
査読の有無	yes
資料タイプ	Journal Article
研究者情報	https://hyokadb02.jimu.kyutech.ac.jp/html/332_ja.html
連携ID	6613

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Photophysical Characterization and BSA Interaction of Direct Ring Carboxy Functionalized Symmetrical squaraine Dyes 利用統計を見る

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Kyushu Institute of Technology Academic Repository

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Photophysical Characterization and BSA Interaction of Direct Ring Carboxy Functionalized Symmetrical squaraine Dyes 利用統計を見る

Kyutacar　九州工業大学学術機関リポジトリ