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Photophysical Characterization and BSA Interaction of Direct Ring Carboxy Functionalized Symmetrical squaraine Dyes
http://hdl.handle.net/10228/00006532
http://hdl.handle.net/10228/000065326362a355-a928-4d08-9f8a-1768fd1a6f23
| 名前 / ファイル | ライセンス | アクション |
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JPCS924_012006.pdf (1.1 MB)
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| Item type | 学術雑誌論文 = Journal Article(1) | |||||||||||
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| 公開日 | 2018-01-29 | |||||||||||
| 資源タイプ | ||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
| 資源タイプ | journal article | |||||||||||
| タイトル | ||||||||||||
| タイトル | Photophysical Characterization and BSA Interaction of Direct Ring Carboxy Functionalized Symmetrical squaraine Dyes | |||||||||||
| 言語 | en | |||||||||||
| 言語 | ||||||||||||
| 言語 | eng | |||||||||||
| 著者 |
Saikiran, Maryala
× Saikiran, Maryala× パンディ, シャム スディル
WEKO
6311
× 早瀬, 修二× 加藤, 珠樹 |
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| 抄録 | ||||||||||||
| 内容記述タイプ | Abstract | |||||||||||
| 内容記述 | A series of far-red sensitive symmetrical squaraine dyes bearing direct –COOH functionalized indole ring were synthesized, characterized and subjected to photophysical investigations. These symmetrical squaraine dyes were then subjected to investigate their interaction with bovine serum albumin (BSA) in Phosphate buffer solutions. All the squaraine dyes under investigation exhibit intense and sharp optical absorption mainly in the far-red wavelength region from 550 nm -700 nm having very high molar extinction coefficients from 1.3 × 105 dm3.mol−1.cm−1. A very small Stokes shift of 10-17 nm indicates the rigid conformational structure of squaraine chromophore. Interaction of these dyes with BSA leads to not only enhanced emission intensity but also bathochromically shifted absorption maximum due to formation of dye-BSA conjugate. These dyes bind strongly with BSA having about an order of magnitude higher binding constant as compared to the reported squaraine dyes. Amongst the symmetrical squaraine dyes investigated in this work one bearing substituents like trifluorobutyl as alkyl chain at N-position of indole ring and carboxylic acid on benzene ring at the terminal (SQ-26) exhibited highest association with the BSA having very high binding constant 8.01 × 106 M−1. | |||||||||||
| 言語 | en | |||||||||||
| 備考 | ||||||||||||
| 内容記述タイプ | Other | |||||||||||
| 内容記述 | 12th International Conference on Nanomolecular Electronics (ICNME-2016), December 14-16, 2016, Kobe International Conference Center, Kobe, Japan | |||||||||||
| 書誌情報 |
en : Journal of Physics: Conference Series 巻 924, 号 1, p. 012006-1-012006-10, 発行日 2017-11 |
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| 出版社 | ||||||||||||
| 出版者 | IOP Publishing | |||||||||||
| 言語 | en | |||||||||||
| DOI | ||||||||||||
| 関連タイプ | isIdenticalTo | |||||||||||
| 識別子タイプ | DOI | |||||||||||
| 関連識別子 | https://doi.org/10.1088/1742-6596/924/1/012006 | |||||||||||
| ISSN | ||||||||||||
| 収録物識別子タイプ | PISSN | |||||||||||
| 収録物識別子 | 1742-6588 | |||||||||||
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| 収録物識別子タイプ | EISSN | |||||||||||
| 収録物識別子 | 1742-6596 | |||||||||||
| 著作権関連情報 | ||||||||||||
| 権利情報Resource | https://creativecommons.org/licenses/by/3.0/ | |||||||||||
| 権利情報 | Content from this work may be used under the terms of the Creative Commons Attribution 3.0 licence. Any further distribution of this work must maintain attribution to the author(s) and the title of the work, journal citation and DOI. | |||||||||||
| 出版タイプ | ||||||||||||
| 出版タイプ | VoR | |||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||
| 査読の有無 | ||||||||||||
| 値 | yes | |||||||||||
| 研究者情報 | ||||||||||||
| URL | https://hyokadb02.jimu.kyutech.ac.jp/html/332_ja.html | |||||||||||
| 論文ID（連携） | ||||||||||||
| 値 | 10309950 | |||||||||||
| 連携ID | ||||||||||||
| 値 | 6613 | |||||||||||
