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Adsorption characteristics of bovine serum albumin onto alumina with a specific crystalline structure
http://hdl.handle.net/10228/5927
http://hdl.handle.net/10228/5927daeb5059-bc2d-4840-919c-114597d24ebc
| 名前 / ファイル | ライセンス | アクション |
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JMSMM25_453.pdf (1.1 MB)
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| Item type | 学術雑誌論文 = Journal Article(1) | |||||||||||||
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| 公開日 | 2016-12-02 | |||||||||||||
| 資源タイプ | ||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||
| 資源タイプ | journal article | |||||||||||||
| タイトル | ||||||||||||||
| タイトル | Adsorption characteristics of bovine serum albumin onto alumina with a specific crystalline structure | |||||||||||||
| 言語 | en | |||||||||||||
| 言語 | ||||||||||||||
| 言語 | eng | |||||||||||||
| 著者 |
Kawashita, Masakazu
× Kawashita, Masakazu× Hayashi, Junpei× Li, Zhixia× 宮崎, 敏樹
WEKO
6369
× Hashimoto, Masami× Hihara, Hiroki× Kanetaka, Hiroyasu |
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| 抄録 | ||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||
| 内容記述 | Bone cement containing alumina particles with a specific crystalline structure exhibits the ability to bond with bone. These particles (AL-P) are mainly composed of delta-type alumina (δ-Al2O3). It is likely that some of the proteins present in the body environment are adsorbed onto the cement and influence the expression of its bioactivity. However, the effect that this adsorption of proteins has on the bone-bonding mechanism of bone cement has not yet been elucidated. In this study, we investigated the characteristics of the adsorption of bovine serum albumin (BSA) onto AL-P and compared them with those of its adsorption onto hydroxyapatite (HA), which also exhibits bone-bonding ability, as well as with those of adsorption onto alpha-type alumina (α-Al2O3), which does not bond with bone. The adsorption characteristics of BSA onto AL-P were very different from those onto α-Al2O3 but quite similar to those onto HA. It is speculated that BSA is adsorbed onto AL-P and HA by interionic interactions, while it is adsorbed onto α-Al2O3 by electrostatic attraction. The results suggest that the specific adsorption of albumin onto implant materials might play a role in the expression of the bone-bonding abilities of the materials. | |||||||||||||
| 言語 | en | |||||||||||||
| 書誌情報 |
en : Journal of Materials Science: Materials in Medicine 巻 25, 号 2, p. 453-459, 発行日 2013-11-02 |
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| 出版社 | ||||||||||||||
| 出版者 | Springer | |||||||||||||
| DOI | ||||||||||||||
| 関連タイプ | isVersionOf | |||||||||||||
| 識別子タイプ | DOI | |||||||||||||
| 関連識別子 | https://doi.org/10.1007/s10856-013-5086-z | |||||||||||||
| NCID | ||||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||||
| 収録物識別子 | AA10761712 | |||||||||||||
| ISSN | ||||||||||||||
| 収録物識別子タイプ | PISSN | |||||||||||||
| 収録物識別子 | 0957-4530 | |||||||||||||
| ISSN | ||||||||||||||
| 収録物識別子タイプ | EISSN | |||||||||||||
| 収録物識別子 | 1573-4838 | |||||||||||||
| 著作権関連情報 | ||||||||||||||
| 権利情報 | Springer | |||||||||||||
| 著作権関連情報 | ||||||||||||||
| 権利情報 | The final publication is available at Springer via http://dx.doi.org/10.1007/s10856-013-5086-z | |||||||||||||
| 出版タイプ | ||||||||||||||
| 出版タイプ | AM | |||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||||||||
| 査読の有無 | ||||||||||||||
| 値 | yes | |||||||||||||
| 研究者情報 | ||||||||||||||
| URL | https://hyokadb02.jimu.kyutech.ac.jp/html/323_ja.html | |||||||||||||
| 連携ID | ||||||||||||||
| 値 | 5853 | |||||||||||||
