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Photophysical characterization and BSA interaction of the direct ring carboxy functionalized unsymmetrical NIR cyanine dyes
http://hdl.handle.net/10228/00007049
http://hdl.handle.net/10228/00007049888008ae-5da0-4c9e-b5f5-98afbe4dd683
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
10306280.pdf (693.2 kB)
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| アイテムタイプ | 学術雑誌論文 = Journal Article(1) | |||||||||||
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| 公開日 | 2019-02-20 | |||||||||||
| 資源タイプ | ||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
| 資源タイプ | journal article | |||||||||||
| タイトル | ||||||||||||
| タイトル | Photophysical characterization and BSA interaction of the direct ring carboxy functionalized unsymmetrical NIR cyanine dyes | |||||||||||
| 言語 | ||||||||||||
| 言語 | eng | |||||||||||
| 著者 |
Saikiran, Maryala
× Saikiran, Maryala× Sato, Daisuke× パンディ, シャム スディル
WEKO
6311
× Ohta, Takeshi× 早瀬, 修二× 加藤, 珠樹 |
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| 抄録 | ||||||||||||
| 内容記述タイプ | Abstract | |||||||||||
| 内容記述 | Novel near infrared (NIR) sensitive unsymmetrical cyanine dyes bearing direct –COOH functionalized indole ring were synthesized, characterized and subjected to photophysical investigations. These unsymmetrical cyanine dyes were then subjected to investigate their interaction with bovine serum albumin (BSA) as a model protein in Phosphate buffer solutions. Apart from NIR absorption and emission with high molar extinction coefficients they exhibit a blue shift in PBS solution owing to their enhanced dye aggregation. Interaction of these dyes with BSA leads to not only enhanced emission intensity but also bathochromically shifted absorption maximum due to formation of dye-BSA conjugate. These dyes bind strongly with BSA having about an order of magnitude higher binding constant as compared to the typical cyanine dyes. Amongst the unsymmetrical cyanine dyes investigated in this work one bearing substituents like Iodo and carboxylic acid in the terminal Indole rings (UCD-3) exhibited highest association with the BSA having very high binding constant of 1.01 × 107 M−1. | |||||||||||
| 書誌情報 |
Dyes and Pigments 巻 140, p. 6-13, 発行日 2017-01-11 |
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| 出版社 | ||||||||||||
| 出版者 | Elsevier | |||||||||||
| DOI | ||||||||||||
| 関連タイプ | isVersionOf | |||||||||||
| 識別子タイプ | DOI | |||||||||||
| 関連識別子 | info:doi/10.1016/j.dyepig.2017.01.015 | |||||||||||
| 日本十進分類法 | ||||||||||||
| 主題Scheme | NDC | |||||||||||
| 主題 | 577 | |||||||||||
| NCID | ||||||||||||
| 収録物識別子タイプ | NCID | |||||||||||
| 収録物識別子 | AA00161945 | |||||||||||
| ISSN | ||||||||||||
| 収録物識別子タイプ | ISSN | |||||||||||
| 収録物識別子 | 0143-7208 | |||||||||||
| ISSN | ||||||||||||
| 収録物識別子タイプ | ISSN | |||||||||||
| 収録物識別子 | 1873-3743 | |||||||||||
| 著作権関連情報 | ||||||||||||
| 権利情報 | Copyright (c) 2017 Elsevier Ltd. | |||||||||||
| 出版タイプ | ||||||||||||
| 出版タイプ | AM | |||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||||||
| 査読の有無 | ||||||||||||
| 値 | yes | |||||||||||
| 研究者情報 | ||||||||||||
| URL | https://hyokadb02.jimu.kyutech.ac.jp/html/332_ja.html | |||||||||||
| 論文ID（連携） | ||||||||||||
| 値 | 10301991 | |||||||||||
| 連携ID | ||||||||||||
| 値 | 6612 | |||||||||||
| 情報源 | ||||||||||||
| 識別子タイプ | DOI | |||||||||||
| 関連識別子 | https://doi.org/10.1016/j.dyepig.2017.01.015 | |||||||||||
| 関連名称 | https://doi.org/10.1016/j.dyepig.2017.01.015 | |||||||||||
