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Seeding Public Goods Is Essential for Maintaining Cooperation in Pseudomonas aeruginosa
http://hdl.handle.net/10228/00007443
http://hdl.handle.net/10228/0000744394e7d753-839f-4f5a-9f5c-5bed3fb65bf5
| 名前 / ファイル | ライセンス | アクション |
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fmicb_2019_02322.pdf (982.1 kB)
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| Item type | 学術雑誌論文 = Journal Article(1) | |||||||||||||
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| 公開日 | 2019-11-20 | |||||||||||||
| 資源タイプ | ||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||
| 資源タイプ | journal article | |||||||||||||
| タイトル | ||||||||||||||
| タイトル | Seeding Public Goods Is Essential for Maintaining Cooperation in Pseudomonas aeruginosa | |||||||||||||
| 言語 | ||||||||||||||
| 言語 | eng | |||||||||||||
| 著者 |
Loarca, Daniel
× Loarca, Daniel× Díaz, Dánae× Quezada, Héctor× Guzmán-Ortiz, Ana Laura× Rebollar-Ruiz, Abril× Fernández Presas, Ana María× Ramírez-Peris, Jimena× Franco-Cendejas, Rafael× 前田, 憲成
WEKO
649
× Wood, Thomas K.× García-Contreras, Rodolfo |
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| 抄録 | ||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||
| 内容記述 | Quorum sensing in Pseudomonas aeruginosa controls the production of costly public goods such as exoproteases. This cooperative behavior is susceptible to social cheating by mutants that do not invest in the exoprotease production but assimilate the amino acids and peptides derived by the hydrolysis of proteins in the extracellular media. In sequential cultures with protein as the sole carbon source, these social cheaters are readily selected and often reach equilibrium with the exoprotease producers. Nevertheless, an excess of cheaters causes the collapse of population growth. In this work, using the reference strain PA14 and a clinical isolate from a burn patient, we demonstrate that the initial amount of public goods (exoprotease) that comes with the inoculum in each sequential culture is essential for maintaining population growth and that eliminating the exoprotease in the inoculum leads to rapid population collapse. Therefore, our results suggest that sequential washes should be combined with public good inhibitors to more effectively combat P. aeruginosa infections. | |||||||||||||
| 書誌情報 |
Frontiers in Microbiology 巻 10, p. 2322-1-2322-8, 発行日 2019-10-09 |
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| 出版者 | Frontiers | |||||||||||||
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| 関連タイプ | isIdenticalTo | |||||||||||||
| 識別子タイプ | DOI | |||||||||||||
| 関連識別子 | info:doi/10.3389/fmicb.2019.02322 | |||||||||||||
| ISSN | ||||||||||||||
| 収録物識別子タイプ | ISSN | |||||||||||||
| 収録物識別子 | 1664-302X | |||||||||||||
| 著作権関連情報 | ||||||||||||||
| 権利情報 | Copyright (c) 2019 Loarca, Díaz, Quezada, Guzmán-Ortiz, Rebollar-Ruiz, Presas, Ramírez-Peris, Franco-Cendejas, Maeda, Wood and García-Contreras. | |||||||||||||
| 著作権関連情報 | ||||||||||||||
| 権利情報 | Creative Commons Attribution License (CC BY). | |||||||||||||
| 著作権関連情報 | ||||||||||||||
| 権利情報 | http://creativecommons.org/licenses/by/4.0/ | |||||||||||||
| 出版タイプ | ||||||||||||||
| 出版タイプ | VoR | |||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||
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| 値 | yes | |||||||||||||
| 研究者情報 | ||||||||||||||
| URL | https://hyokadb02.jimu.kyutech.ac.jp/html/333_ja.html | |||||||||||||
| 論文ID（連携） | ||||||||||||||
| 値 | 10347369 | |||||||||||||
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| 値 | 7945 | |||||||||||||
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| 識別子タイプ | DOI | |||||||||||||
| 関連識別子 | https://doi.org/10.3389/fmicb.2019.02322 | |||||||||||||
| 関連名称 | https://doi.org/10.3389/fmicb.2019.02322 | |||||||||||||
