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Detection of Tetraplex DNA and Detection by Tetraplex DNA
http://hdl.handle.net/10228/00008215
http://hdl.handle.net/10228/00008215e47df760-abfc-49a4-9632-72724a574842
名前 / ファイル | ライセンス | アクション |
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analsci.20SAR09.pdf (4.0 MB)
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Item type | 学術雑誌論文 = Journal Article(1) | |||||||||||
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公開日 | 2021-04-22 | |||||||||||
資源タイプ | ||||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
資源タイプ | journal article | |||||||||||
タイトル | ||||||||||||
タイトル | Detection of Tetraplex DNA and Detection by Tetraplex DNA | |||||||||||
言語 | ||||||||||||
言語 | eng | |||||||||||
著者 |
竹中, 繁織
× 竹中, 繁織
WEKO
6749
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抄録 | ||||||||||||
内容記述タイプ | Abstract | |||||||||||
内容記述 | G-quardruplex (G4) DNA forms through the gathering together of G-quartet planes formed with four guanine (G) bases. G4 DNA stabilizes with potassium ions (K+) by coordination with the G-quartet center. Fluorometric G4 DNA carrying the fluorescence resonance energy transfer (FRET) chromophore pair at both termini has been applied for the fluorometric sensing or imaging of K+ under a homogeneous aqueous medium. This system has realized non-conventional K+ selectivity over the sodium ion (Na+). The selectivity of the fluorescence G4 was converted to Na+ from K+ with a modification of its sequence. On the other hand, G4 DNA detection has been achieved in terms of cancer diagnosis because of a strong relationship of G4 DNA and cancer development. Ligands interacting with G4 are expected to have anti-cancer potential. In addition, fluorometric G4 ligands have been developed and tested as tools for the dynamic monitoring of G4 in living cells. Moreover, fluorometric G4 DNA has been utilized to evaluate the G4 ligand performance. | |||||||||||
書誌情報 |
Analytical Sciences 巻 37, 号 1, p. 9-15, 発行日 2020-10-30 |
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出版社 | ||||||||||||
出版者 | 日本分析化学会 | |||||||||||
DOI | ||||||||||||
関連タイプ | isIdenticalTo | |||||||||||
識別子タイプ | DOI | |||||||||||
関連識別子 | https://doi.org/10.2116/analsci.20SAR09 | |||||||||||
日本十進分類法 | ||||||||||||
主題Scheme | NDC | |||||||||||
主題 | 467 | |||||||||||
NCID | ||||||||||||
収録物識別子タイプ | NCID | |||||||||||
収録物識別子 | AA10500785 | |||||||||||
ISSN | ||||||||||||
収録物識別子タイプ | ISSN | |||||||||||
収録物識別子 | 1348-2246 | |||||||||||
ISSN | ||||||||||||
収録物識別子タイプ | ISSN | |||||||||||
収録物識別子 | 0910-6340 | |||||||||||
著作権関連情報 | ||||||||||||
権利情報 | Copyright (c) 2021 by The Japan Society for Analytical Chemistry | |||||||||||
キーワード | ||||||||||||
主題Scheme | Other | |||||||||||
主題 | G-quardruplex (G4) | |||||||||||
キーワード | ||||||||||||
主題Scheme | Other | |||||||||||
主題 | potassium ion | |||||||||||
キーワード | ||||||||||||
主題Scheme | Other | |||||||||||
主題 | sodium ion | |||||||||||
キーワード | ||||||||||||
主題Scheme | Other | |||||||||||
主題 | fluorometric sensing | |||||||||||
キーワード | ||||||||||||
主題Scheme | Other | |||||||||||
主題 | telomere DNA | |||||||||||
キーワード | ||||||||||||
主題Scheme | Other | |||||||||||
主題 | telomerase | |||||||||||
キーワード | ||||||||||||
主題Scheme | Other | |||||||||||
主題 | cancer diagnosis | |||||||||||
出版タイプ | ||||||||||||
出版タイプ | VoR | |||||||||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||
査読の有無 | ||||||||||||
値 | yes | |||||||||||
研究者情報 | ||||||||||||
https://hyokadb02.jimu.kyutech.ac.jp/html/97_ja.html | ||||||||||||
論文ID(連携) | ||||||||||||
10363500 | ||||||||||||
連携ID | ||||||||||||
8727 |