WEKO3
アイテム
Application of naphthalene diimide in biotechnology
http://hdl.handle.net/10228/00008242
http://hdl.handle.net/10228/00008242ae7f4bb0-73ec-4cec-9ed1-308a515f6001
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
10363499.pdf (2.6 MB)
|
|
| アイテムタイプ | 学術雑誌論文 = Journal Article(1) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 公開日 | 2021-05-10 | |||||||||||||
| 資源タイプ | ||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||
| 資源タイプ | journal article | |||||||||||||
| タイトル | ||||||||||||||
| タイトル | Application of naphthalene diimide in biotechnology | |||||||||||||
| 言語 | en | |||||||||||||
| 言語 | ||||||||||||||
| 言語 | eng | |||||||||||||
| 著者 |
竹中, 繁織
× 竹中, 繁織
WEKO
6749
|
|||||||||||||
| 抄録 | ||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||
| 内容記述 | Naphthalene diimide (NDI) is an electron-deficient, robust, and planar molecule. These characteristics make it highly applicable to electronic devices that take advantage of their electric character, for imide group-based supramolecular materials that utilize hydrogen bonding, or for sensing materials with a combination of functional groups. Water-soluble NDI binds to a DNA duplex via the threading intercalation mode. Such NDI has enabled the development of unique DNA analytical techniques, functional DNA polymers, and supramolecular polymers. A ferrocene-containing NDI, possessing electrochemically active sites, has been applied to an electrochemical gene detection system and utilized in the precision analysis of genes and single nucleotide polymorphisms. Recently, a DNA quadruplex was identified as one of the noncanonical DNA structures formed by a guanine quartet (G4). The latter serves as one of the control units of gene expression and is associated with cancer development. A stable complex was formed between electron-deficient NDI and the electron-rich G4 planes. Since the G4 stabilizer is recognized as an anticancer agent with relatively few side effects, NDI derivatives may serve as potential candidates for anticancer therapeutics or for designing a unique cancer-detection system. | |||||||||||||
| 言語 | en | |||||||||||||
| 書誌情報 |
en : Polymer Journal 巻 53, 号 3, p. 415-427, 発行日 2020-11-10 |
|||||||||||||
| 出版社 | ||||||||||||||
| 出版者 | Nature Publishing Group | |||||||||||||
| DOI | ||||||||||||||
| 関連タイプ | isVersionOf | |||||||||||||
| 識別子タイプ | DOI | |||||||||||||
| 関連識別子 | https://doi.org/10.1038/s41428-020-00434-2 | |||||||||||||
| 日本十進分類法 | ||||||||||||||
| 主題Scheme | NDC | |||||||||||||
| 主題 | 579 | |||||||||||||
| ISSN | ||||||||||||||
| 収録物識別子タイプ | PISSN | |||||||||||||
| 収録物識別子 | 0032-3896 | |||||||||||||
| ISSN | ||||||||||||||
| 収録物識別子タイプ | EISSN | |||||||||||||
| 収録物識別子 | 1349-0540 | |||||||||||||
| 著作権関連情報 | ||||||||||||||
| 権利情報 | Copyright (c) 2020 The Society of Polymer Science, Japan | |||||||||||||
| キーワード | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | Biochemistry | |||||||||||||
| キーワード | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | Cancer | |||||||||||||
| キーワード | ||||||||||||||
| 主題Scheme | Other | |||||||||||||
| 主題 | Nanobiotechnology | |||||||||||||
| 出版タイプ | ||||||||||||||
| 出版タイプ | AM | |||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||||||||
| 査読の有無 | ||||||||||||||
| 値 | yes | |||||||||||||
| 研究者情報 | ||||||||||||||
| URL | https://hyokadb02.jimu.kyutech.ac.jp/html/97_ja.html | |||||||||||||
| 論文ID（連携） | ||||||||||||||
| 値 | 10363499 | |||||||||||||
| 連携ID | ||||||||||||||
| 値 | 8740 | |||||||||||||
