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Synthesis and in vitro biodegradation of pure octacalcium phosphate spheres
http://hdl.handle.net/10228/00007990
http://hdl.handle.net/10228/0000799040ab2562-ac61-4225-be8f-14bb08ab8a5a
名前 / ファイル | ライセンス | アクション |
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ijac.13371.pdf (2.3 MB)
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Item type | 学術雑誌論文 = Journal Article(1) | |||||||||||
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公開日 | 2020-12-21 | |||||||||||
資源タイプ | ||||||||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||
資源タイプ | journal article | |||||||||||
タイトル | ||||||||||||
タイトル | Synthesis and in vitro biodegradation of pure octacalcium phosphate spheres | |||||||||||
言語 | ||||||||||||
言語 | eng | |||||||||||
著者 |
Tripathi, Garima
× Tripathi, Garima× 宮崎, 敏樹
WEKO
6369
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抄録 | ||||||||||||
内容記述タイプ | Abstract | |||||||||||
内容記述 | Octacalcium phosphate (OCP) is a key precursor of biological apatite in hard tissues with excellent osteoconductive and biodegradable properties for bone regeneration. OCP spherical granules are expected to be useful as drug delivery carriers, since OCP has high specific surface area. Although there have been some reports of OCP sphere preparation, methods for preparing pure OCP spheres are limited. The objective of this study is the preparation of spherical granules of pure OCP and assessment of their in vitro biodegradation in physiological conditions. We successfully prepared spherical pure OCP granules with a size of ~500 µm without any organic additives by simple immersion of α‐tricalcium phosphate spherical granules in pH 5.0 acetate buffered solutions at 60°C. The granules had core‐shell structure composed of OCP crystals different particle size. The spherical granules showed 20%‐40% in vitro degradation in physiological conditions; however, the phase transition of OCP was not significantly observed. | |||||||||||
書誌情報 |
International Journal of Applied Ceramic Technology 巻 17, 号 1, p. 372-379, 発行日 2019-12-19 |
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出版社 | ||||||||||||
出版者 | Blackwell Publishing Ltd. | |||||||||||
DOI | ||||||||||||
関連タイプ | isVersionOf | |||||||||||
識別子タイプ | DOI | |||||||||||
関連識別子 | https://doi.org/10.1111/ijac.13371 | |||||||||||
日本十進分類法 | ||||||||||||
主題Scheme | NDC | |||||||||||
主題 | 497 | |||||||||||
NCID | ||||||||||||
収録物識別子タイプ | NCID | |||||||||||
収録物識別子 | AA11926159 | |||||||||||
ISSN | ||||||||||||
収録物識別子タイプ | ISSN | |||||||||||
収録物識別子 | 1546-542X | |||||||||||
ISSN | ||||||||||||
収録物識別子タイプ | ISSN | |||||||||||
収録物識別子 | 1744-7402 | |||||||||||
著作権関連情報 | ||||||||||||
権利情報 | Copyright (c) 2019 The American Ceramic Society | |||||||||||
キーワード | ||||||||||||
主題Scheme | Other | |||||||||||
主題 | Acetate buffer treatment | |||||||||||
キーワード | ||||||||||||
主題Scheme | Other | |||||||||||
主題 | in vitro biodegradation | |||||||||||
キーワード | ||||||||||||
主題Scheme | Other | |||||||||||
主題 | Pure OCP sphere | |||||||||||
キーワード | ||||||||||||
主題Scheme | Other | |||||||||||
主題 | α‐TCP | |||||||||||
出版タイプ | ||||||||||||
出版タイプ | AM | |||||||||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||||||
査読の有無 | ||||||||||||
値 | yes | |||||||||||
研究者情報 | ||||||||||||
https://hyokadb02.jimu.kyutech.ac.jp/html/323_ja.html | ||||||||||||
論文ID(連携) | ||||||||||||
10348421 | ||||||||||||
連携ID | ||||||||||||
8011 | ||||||||||||
著者別名 | ||||||||||||
姓名 | Tripathi, G. | |||||||||||
著者別名 | ||||||||||||
姓名 | Miyazaki, Toshiki | |||||||||||
言語 | en | |||||||||||
姓名 | 宮崎, 敏樹 | |||||||||||
言語 | ja | |||||||||||
姓名 | ミヤザキ, トシキ | |||||||||||
言語 | ja-Kana |