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Apatite-forming ability of vinylphosphonic acid-based copolymer in simulated body fluid: effects of phosphate group content
http://hdl.handle.net/10228/00006360
http://hdl.handle.net/10228/000063601f15704a-23db-41d3-bba2-7ffc367cc36e
| 名前 / ファイル | ライセンス | アクション |
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JMSM-D-16-00098_R1.pdf (685.6 kB)
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| アイテムタイプ | 学術雑誌論文 = Journal Article(1) | |||||||||||||||||||||
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| 公開日 | 2017-09-01 | |||||||||||||||||||||
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| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||||||
| 資源タイプ | journal article | |||||||||||||||||||||
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| タイトル | Apatite-forming ability of vinylphosphonic acid-based copolymer in simulated body fluid: effects of phosphate group content | |||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||
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| 言語 | eng | |||||||||||||||||||||
| 著者 |
Hamai, Ryo
× Hamai, Ryo× 城崎, 由紀
WEKO
15664
× 宮崎, 敏樹
WEKO
6369
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| 内容記述タイプ | Abstract | |||||||||||||||||||||
| 内容記述 | Phosphate groups on materials surfaces are known to contribute to apatite formation upon exposure of the materials in simulated body fluid and improved affinity of the materials for osteoblast-like cells. Typically, polymers containing phosphate groups are organic matrices consisting of apatite–polymer composites prepared by biomimetic process using simulated body fluid. Ca2+ incorporation into the polymer accelerates apatite formation in simulated body fluid owing because of increase in the supersaturation degree, with respect to apatite in simulated body fluid, owing to Ca2+ release from the polymer. However, the effects of phosphate content on the Ca2+ release and apatite-forming abilities of copolymers in simulated body fluid are rather elusive. In this study, a phosphate-containing copolymer prepared from vinylphosphonic acid, 2-hydroxyethyl methacrylate, and triethylene glycol dimethacrylate was examined. The release of Ca2+ in Tris-NaCl buffer and simulated body fluid increased as the additive amount of vinylphosphonic acid increased. However, apatite formation was suppressed as the phosphate groups content increased despite the enhanced release of Ca2+ from the polymer. This phenomenon was reflected by changes in the surface zeta potential. Thus, it was concluded that the apatite-forming ability of vinylphosphonic acid-2-hydroxyethyl methacrylate-triethylene glycol dimethacrylate copolymer treated with CaCl2 solution was governed by surface state rather than Ca2+ release in simulated body fluid. | |||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||
| 書誌情報 |
en : Journal of Materials Science: Materials in Medicine 巻 27, 号 10, p. 152, 発行日 2016-09-01 |
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| 出版者 | Springer | |||||||||||||||||||||
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| 関連タイプ | isVersionOf | |||||||||||||||||||||
| 識別子タイプ | DOI | |||||||||||||||||||||
| 関連識別子 | https://doi.org/10.1007/s10856-016-5761-y | |||||||||||||||||||||
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| 収録物識別子タイプ | NCID | |||||||||||||||||||||
| 収録物識別子 | AA10761712 | |||||||||||||||||||||
| ISSN | ||||||||||||||||||||||
| 収録物識別子タイプ | PISSN | |||||||||||||||||||||
| 収録物識別子 | 0957-4530 | |||||||||||||||||||||
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| 収録物識別子タイプ | EISSN | |||||||||||||||||||||
| 収録物識別子 | 1573-4838 | |||||||||||||||||||||
| 著作権関連情報 | ||||||||||||||||||||||
| 権利情報 | Springer Science+Business Media New York 2016 | |||||||||||||||||||||
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| 権利情報 | The final publication is available at Springer via http://dx.doi.org/10.1007/s10856-016-5761-y | |||||||||||||||||||||
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| 出版タイプ | AM | |||||||||||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||||||||||||||||||
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| 値 | yes | |||||||||||||||||||||
| 研究者情報 | ||||||||||||||||||||||
| URL | https://hyokadb02.jimu.kyutech.ac.jp/html/323_ja.html | |||||||||||||||||||||
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| 値 | 10297079 | |||||||||||||||||||||
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| 値 | 5515 | |||||||||||||||||||||
