WEKO3
アイテム
Preparation and Characterization of Encapsulated Tamoxifen Citrate-Magnetite Nanoparticle via Oil in Water Emulsion Evaporation Technique
http://hdl.handle.net/10228/00008766
http://hdl.handle.net/10228/0000876642ccccf3-0367-44c3-a6b5-b2799d4ed75a
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
NMRJ_Volume6_Issue4_Pages337-346.pdf (1.1 MB)
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| アイテムタイプ | 学術雑誌論文 = Journal Article(1) | |||||||||||||||||||||
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| 公開日 | 2022-03-14 | |||||||||||||||||||||
| 資源タイプ | ||||||||||||||||||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||||||||||||||||||
| 資源タイプ | journal article | |||||||||||||||||||||
| タイトル | ||||||||||||||||||||||
| タイトル | Preparation and Characterization of Encapsulated Tamoxifen Citrate-Magnetite Nanoparticle via Oil in Water Emulsion Evaporation Technique | |||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||
| その他のタイトル | ||||||||||||||||||||||
| その他のタイトル | Preparation and Characterization of PLGA Encapsulated Tamoxifen Citrate-Magnetite Nanoparticle Via Oil in Water Emulsion Evaporation Technique | |||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||
| 言語 | ||||||||||||||||||||||
| 言語 | eng | |||||||||||||||||||||
| 著者 |
Albert, Emmellie Laura
× Albert, Emmellie Laura× Abdullah, Che Azurahanim Che× Bahmanrokh, Ghazaleh× 城崎, 由紀
WEKO
15664
× 宮崎, 敏樹
WEKO
6369
× Yaacob, Siti Norzulfikaini |
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| 抄録 | ||||||||||||||||||||||
| 内容記述タイプ | Abstract | |||||||||||||||||||||
| 内容記述 | Current research had successfully encapsulated magnetic nanoparticles (MNP) with selective estrogen receptor drug tamoxifen citrate (TAM) using Poly (d,l-lactice-co-glycolide acid) (PLGA 75:25) via oil in water emulsion technique. TAM is a good example of a drug that is difficult to dissolve. TAM is currently approved for the treatment of hormone-sensitive and early-stage breast cancer as an adjuvant endocrine therapy. The majority of the prescription medicine in today market is made up of poorly soluble, bioavailable, and quickly metabolized and eliminated drug which is a continuously challenges up to these days. Therefore, it is imperative to overcome this disadvantages by encapsulating TAM inside PLGA together with MNP for improved drug delivery. The MNP coated with oleic acid (OA) was synthesized using co-precipitation method and it is known as OAMNP. The fabricated nanohybrid is known as TAM-PLGA-OAMNP where the TAM was encapsulated together with OAMNP within PLGA. XRD results showed that OAMNP is Fe3O4. FTIR spectra revealed that the TAM was successfully encased into the PLGA structure. TAM-PLGA-OAMNP average size is about 131 ± 28 nm as shown in TEM results. The nanohybrid nanoparticles showed the absence of hysteresis loop indicative of superparamagnetic properties. | |||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||
| 書誌情報 |
en : Nanomedicine Research Journal 巻 6, 号 4, p. 337-346, 発行日 2021-11-01 |
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| 出版社 | ||||||||||||||||||||||
| 出版者 | Iranian Society of Nanomedicine | |||||||||||||||||||||
| 言語 | en | |||||||||||||||||||||
| DOI | ||||||||||||||||||||||
| 関連タイプ | isIdenticalTo | |||||||||||||||||||||
| 識別子タイプ | DOI | |||||||||||||||||||||
| 関連識別子 | https://doi.org/10.22034/NMRJ.2021.04.003 | |||||||||||||||||||||
| 日本十進分類法 | ||||||||||||||||||||||
| 主題Scheme | NDC | |||||||||||||||||||||
| 主題 | 431 | |||||||||||||||||||||
| 著作権関連情報 | ||||||||||||||||||||||
| 権利情報 | This work is licensed under the Creative Commons Attribution 4.0 International License. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. | |||||||||||||||||||||
| キーワード | ||||||||||||||||||||||
| 主題Scheme | Other | |||||||||||||||||||||
| 主題 | Magnetite nanoparticle | |||||||||||||||||||||
| キーワード | ||||||||||||||||||||||
| 主題Scheme | Other | |||||||||||||||||||||
| 主題 | Tamoxifen citrate | |||||||||||||||||||||
| キーワード | ||||||||||||||||||||||
| 主題Scheme | Other | |||||||||||||||||||||
| 主題 | Poly (d l-lactice-co-glycolide acid) | |||||||||||||||||||||
| 出版タイプ | ||||||||||||||||||||||
| 出版タイプ | VoR | |||||||||||||||||||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||||||||||||||||||
| 査読の有無 | ||||||||||||||||||||||
| 値 | yes | |||||||||||||||||||||
| 研究者情報 | ||||||||||||||||||||||
| URL | https://hyokadb02.jimu.kyutech.ac.jp/html/323_ja.html | |||||||||||||||||||||
| 論文ID（連携） | ||||||||||||||||||||||
| 値 | 10388679 | |||||||||||||||||||||
| 連携ID | ||||||||||||||||||||||
| 値 | 10193 | |||||||||||||||||||||
